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Published TCIMAIL newest issue No.201
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CAS RN: 302-79-4 | Product Number: R0064
Retinoic Acid
Purity: >93.0%(HPLC)
Synonyms:
- Vitamin A Acid
- all-trans-Retinoic Acid
- Tretinoin
- all-trans-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic Acid
- ATRA
Product Documents:
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| Product Number | R0064 |
Purity / Analysis Method
|
>93.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__0H__2__8O__2 = 300.44 |
| Physical State (20 deg.C) | Solid |
Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Air Sensitive |
Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 302-79-4 |
| Reaxys Registry Number | 2057223 |
| PubChem Substance ID | 87575622 |
| SDBS (AIST Spectral DB) | 21421 |
| Merck Index (14) | 8165 |
| MDL Number | MFCD00001551 |
Specifications
| Appearance | Light yellow to Amber to Dark green powder to crystal |
| Purity(HPLC) | min. 93.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
Properties (reference)
| Melting Point | 180 °C |
| Solubility in water | Insoluble |
| Solubility (soluble in) | Ether |
| Solubility (slightly sol. in) | Chloroform, Alcohol |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H302 : Harmful if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. H360 : May damage fertility or the unborn child. H410 : Very toxic to aquatic life with long lasting effects. |
| Precautionary Statements | P273 : Avoid release to the environment. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P391 : Collect spillage. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. |
Related Laws:
| EC Number | 206-129-0 |
| RTECS# | VH6475000 |
Transport Information:
| UN Number | UN3077 |
| Class | 9 |
| Packing Group | III |
| HS Number | 2936210000 |
Application
Reviews on Molecular Biology of Retionoid Acid
References
- A decade of molecular biology of retinoic acid receptors
- P. Chambon, FASEB J. 1996, 10, 940.
- Gene expression regulation by retinoic acid
- Function of retinoid nuclear receptors: lessons from genetic and pharmacological dissections of the retinoic acid signaling pathway during mouse embryogenesis
- Overview of retinoid metabolism and function
- Retinoic acid in the development, regeneration and maintenance of the nervous system
- Retinoic acid synthesis and signaling during early organogenesis
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