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CAS RN: 145202-66-0 | Product Number: R0181
Rizatriptan Benzoate
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Purity: >98.0%(T)(HPLC)
Synonyms:
- N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethylamine Benzoate
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 50MG |
€73.00
|
2 | 7 |
|
|
| 250MG |
€234.00
|
Contact Us | 21 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | R0181 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__5H__1__9N__5·C__7H__6O__2 = 391.48 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container
|
50MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 145202-66-0 |
| Reaxys Registry Number | 7066526 |
| PubChem Substance ID | 354334261 |
| Merck Index (14) | 8241 |
| MDL Number | MFCD00866224 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 %(total of Ion-Pair) |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 178.0 to 182.0 °C |
Properties (reference)
| Melting Point | 180 °C |
| Solubility in water | Soluble |
| Degree of solubility in water | 53 g/l |
| Solubility (soluble in) | Methanol |
| Solubility (slightly sol. in) | Ethanol |
| Solubility (insoluble in) | Ether |
GHS
Related Laws:
Transport Information:
| HS Number | 2933998090 |
Application
Rizatriptan Benzoate: A Selective Serotonin 5-HT1B/1D Receptor Agonist
Rizatriptan benzoate is a derivative of tryptamine [T0890]. It is a selective serotonin 5-HT1B/1D receptor agonist used in the acute treatment of migraine. (The product is for research purpose only.)
References
- Synthesis and Serotonergic Activity of N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethylamine and Analogs: Potent Agonists for 5-HT1D Receptors
- The novel anti-migraine agent rizatriptan inhibits neurogenic dural vasodilation and extravasation
- Rizatriptan has central antinociceptive effects against durally evoked responses
- Mechanisms of Action of the 5-HT1B/1D Receptor Agonists (a review)
- A review of the 5-HT1B/1D agonist rizatriptan: update on recent research and implications for the future
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