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Published TCIMAIL newest issue No.198
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CAS RN: 5467-74-3 | Product Number: B1858
4-Bromophenylboronic Acid (contains varying amounts of Anhydride)
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Purity:
Synonyms:
- 4-Bromobenzeneboronic Acid (contains varying amounts of Anhydride)
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
€16.00
|
1 | ≥60 |
|
| 5G |
€30.00
|
8 | ≥100 |
|
| 25G |
€106.00
|
2 | ≥100 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | B1858 |
| Molecular Formula / Molecular Weight | C__6H__6BBrO__2 = 200.83 |
| Physical State (20 deg.C) | Solid |
Storage Temperature 
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 5467-74-3 |
| Reaxys Registry Number | 2936347 |
| PubChem Substance ID | 87564746 |
| SDBS (AIST Spectral DB) | 22866 |
| MDL Number | MFCD00002104 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(Neutralization titration) | 97.0 to 110.0 % |
Properties (reference)
| Melting Point | 292 °C |
| Solubility (soluble in) | Methanol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| EC Number | 226-779-9 |
| RTECS# | CY8650000 |
Transport Information:
| HS Number | 2931900090 |
Application
AmpC β-lactamase inhibitor
The primary resistance mechanism of microbes to β-lactam antibiotics is hydrolysis of the antibiotics by β-lactamase.1) 4-Bromophenylboronic acid is one of boronic acid compounds having β-lactamase (AmpC) inhibition activity (Ki = 3.6 ± 0.9 μM).2)
References
- β-Lactamases and β-Lactamase Inhibitors in the 21st Century
- Structure-Based Enhancement of Boronic Acid-Based Inhibitors of AmpC β-Lactamase
- Inhibition of Quorum Sensing in Vibrio harveyi by Boronic Acids
Application
Quorum sensing research
4-Bromophenylboronic acid has been reported to inhibit autoinducer-2 (AI-2) quorum sensing in Vibrio harveyi.
Reference
PubMed Literature
Documents
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Specifications
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