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Published TCIMAIL newest issue No.201
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CAS RN: 39262-14-1 | Product Number: G0590
Ginsenoside C-K
Purity: >95.0%(HPLC)
Synonyms:
- 20(S)-Ginsenoside Ck
- 3β,12β-Dihydroxydammar-24-en-20-yl β-D-Glucopyranoside
Product Documents:
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| Product Number | G0590 |
Purity / Analysis Method
|
>95.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__3__6H__6__2O__8 = 622.88 |
| Physical State (20 deg.C) | Solid |
Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 39262-14-1 |
| Reaxys Registry Number | 5785005 |
| PubChem Substance ID | 468591952 |
| MDL Number | MFCD07772261 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Specific rotation | +37.0 to +41.0 deg(C=1,pyridine) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 178 °C |
GHS
Related Laws:
| RTECS# | LZ5776536 |
Transport Information:
| HS Number | 2938909090 |
Application
Ginsenoside C-K: A Major Deglycosylated Metabolite of Ginsenosides, a Traditional Medicine
Ginsenosides are representative pharmaceutical compounds found in various forms in Panax ginseng, a traditional medicinal plant. Then ginsenoside C-K (compound K) is a major deglycosylated metabolite of ginsenosides transformed by intestinal bacterial flora. And it has been demonstrated such diverse intriguing biological properties as anti-carcinogenic, anti-inflammation, anti-allergic, anti-diabetic, anti-angiogenesis, anti-aging, neuroprotective and hepatoprotective effects. (The product is for research purpose only.)
References
- Intestinal bacterial hydrolysis is required for the appearance of compound K in rat plasma after oral administration of ginsenoside Rb1 from Panax ginseng
- Constitutive β-glucosidases hydrolyzing ginsenoside Rb1 and Rb2 from human intestinal bacteria
- Ginsenoside Rb1 and its metabolite compound K inhibit IRAK-1 activation-The key step of inflammation
- A review of biotransformation and pharmacology of ginsenoside compound K
Product Documents (Note: Some products will not have analytical charts available.)
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