Published TCIMAIL newest issue No.201
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 82586-55-8 | Product Number: Q0082
Quinapril Hydrochloride
×
Purity: >98.0%(T)(HPLC)
Synonyms:
- (S)-2-[[(S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acid Hydrochloride
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 250MG |
€125.00
|
Contact Us | 18 |
|
|
| 1G |
€265.00
|
Contact Us | 25 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | Q0082 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__5H__3__0N__2O__5·HCl = 474.98 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Hygroscopic,Heat Sensitive |
| CAS RN | 82586-55-8 |
| Reaxys Registry Number | 5699760 |
| MDL Number | MFCD00889215 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Specific rotation | +14.0 to +16.0 deg(C=2, methanol) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 130 °C |
| Solubility (insoluble in) | Diethyl ether |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H361 : Suspected of damaging fertility or the unborn child. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
| RTECS# | NW7176000 |
Transport Information:
| HS Number | 2933499090 |
Application
Quinapril Hydrochloride: A Non-Peptide, Non-Sulfhydryl Angiotensin- Converting Enzyme (ACE) Inhibitor
Angiotensin-converting enzyme (ACE) is a peptidyl dipeptidase that catalyzes the conversion of angiotensin I to the vasoconstrictor, angiotensin II. Quinapril hydrochloride is an orally active, non-peptide, non-sulfhydryl angiotensin- converting enzyme (ACE) inhibitor. It is a prodrug and is de-esterified to the principal metabolite, quinaprilat, which is an inhibitor of ACE activity in human subjects and animals. The effects of quinapril in hypertension and in congestive heart failure (CHF) appear to result primarily from the inhibition of circulating and tissue ACE activity, thereby reducing angiotensin II formation. (The product is for research use only.)
References
- Quinapril—A Preclinical Review of the Pharmacology, Pharmacokinetics, and Toxicology
- Quinapril. A review of its pharmacological properties, and therapeutic efficacy in cardiovascular disorders
- Quinapril: A further update of its pharmacology and therapeutic use in cardiovascular disorders
- Improving the detection of degradants and impurities in pharmaceutical drug products by applying mass spectral and chromatographic searching
- Determination of losartan potassium, quinapril hydrochloride and hydrochlorothiazide in pharmaceutical preparations using derivative spectrophotometry and chromatographic-densitometric method
Product Documents (Note: Some products will not have analytical charts available.)
Enter TCI Product Number
Enter KISHIDA Product Number
4-5 alphanumeric characters before the hyphen
7 alphanumeric characters
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
• The requested SDS is not available.
Specifications
The requested specifications are not available.
Please Contact Us for more information.
The requested specifications are not available.
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Incorrect Lot Number. Please input only the 7 alphanumeric characters.
• Please check that the lot number you have entered is correct. It is 4-5 alphanumeric characters before the hyphen. In particular, please check O (letter) or 0 (number) and I (letter) or 1 (number).
• If your information is correct and you are still not able to view the requested certificates, Please Contact Us for more information.
• Please check that the lot number you have entered is correct. It is 7 alphanumeric characters. In particular, please check O (letter) or 0 (number) and I (letter) or 1 (number).
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Incorrect Lot Number. Please input only the 7 alphanumeric characters.
The requested analytical chart is not available. Sorry for the inconvenience.