text.skipToContent text.skipToNavigation

Maximum quantity allowed is 999

Please select the quantity

CAS RN: | Product Number: A2510

Anti-Lewis Y Monoclonal Antibody


Purity:
Synonyms:
Documents:
1VIAL
€331.00
Contact Us 13  

*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).


Note:

Product Information
Volume/Quantity : 0.1 mg
Product Form : Purified mouse monoclonal antibody/IgG3, κ-chain
Buffer : Phosphate buffered-saline (PBS)
Preparation : The antibody is purified from ascites fluid.
Preservative : 0.05% Sodium azide
Stabilizer : None
Immunogen : Immunized with human gastric cancer cells (MKN74), and screened using cancer glycolipids
Specificity : Lewis Y antigen
Clone Name : H18A

Application
ELISA, Flow cytometry, Immunohistochemistry, Western blot, TLC-immunostaining.

Storage
Store at -20 ºC to -80 ºC (Preferably at -80 ºC). It is not recommended storing at 4 ºC. Avoid repeated freezing and thawing.

Related Products
G0386 Goat Anti-Mouse IgG
G0387 Goat Anti-Mouse IgG Biotin Conjugate
G0406 Goat Anti-Mouse IgG FITC Conjugate
G0407 Goat Anti-Mouse IgG HRP Conjugate
G0505 Goat Anti-Mouse IgG DTBTA-Eu3+ Conjugate
G0569 Goat Anti-Mouse IgG R-PE Conjugate

Product Number A2510
Physical State (20 deg.C) Liquid
Storage Temperature -80°C
Condition to Avoid Heat Sensitive
Specifications
Appearance Colorless to Almost colorless clear liquid
Titer(ELISA) to pass test
Properties (reference)
GHS
Related Laws:
Transport Information:
HS Number 3002150000
Application
Anti-Lewis Y Monoclonal Antibody
References

High idiotypic connectivity of the VH7183-encoded antibodies directed to a murine embryonic carbohydrate antigen, Lewis Y, as ascertained by syngenic anti-idiotype monoclonal antibodies.

K. Hirashima, K. Zenita, A. Takada, A. Kitahara, G. Ishihara, R. Harada, K. Ohmori, S. Hirohashi, S. Kyoizumi, M. Akiyama, R. Kannagi, J. Immunol. 1990, 145, 224-232.

Preparation of mouse-human chimeric antibody to an embryonic carbohydrate antigen, Lewis Y.

T. Kaneko, Y. Iba, K. Zenita, K. Shigeta, K. Nakano, W. Itoh, Y. Kurosawa, R. Kannagi, K. Yasukawa, J. Biochem. 1993, 113, 114-117.

Targeted gene transfer for adenocarcinoma using a combination of tumor-specific antibody and tissue-specific promoter.

S. Kurane, J. C. Krauss, E. Watari, R. Kannagi, A. E. Chang, S. Kudoh, Jpn. J. Cancer Res. 1998, 89, 1212-1219.

Transgene expression of alpha(1,2)-fucosyltransferase-I (FUT1) in tumor cells selectively inhibits sialyl-Lewis x expression and binding to E-selectin without affecting synthesis of sialyl-Lewis a or binding to P-selectin.

S. Mathieu, M. Prorok, A.-M. Benoliel, R. Uch, C. Langlet, P. Bongrand, R. Gerolami, A. El-Battari, Am. J. Pathol. 2004, 164, 371-383.

Lewis y antigen is expressed in oral squamous cell carcinoma cell lines and tissues, but disappears in the invasive regions leading to the enhanced malignant properties irrespective of sialyl-Lewis x.

H. Hotta, K. Hamamura, K. Yamashita, H. Shibuya, N. Tokuda, N. Hashimoto, K. Furukawa, N. Yamamoto, H. Hattori, S. Toyokuni, M. Ueda, K. Furukawa, Glycoconj. J. 2013, 30, 585-597.

Reactivities of Lewis antigen monoclonal antibodies with the lipopolysaccharides of Helicobacter pylori strains isolated from patients with gastroduodenal diseases in Japan.

K. Amano, S. Hayashi, T. Kubota, N. Fujii, S. Yokota, Clin. Diagn. Lab. Immunol. 1997, 4, 540-544.

Developmental changes in the biochemical and immunological characters of the carbohydrate moiety of neuroglycan C, a brain-specific chondroitin sulfate proteoglycan.

T. Shuo, S. Aono, F. Matsui, Y. Tokita, H. Maeda, K. Shimada, A. Oohira, Glycoconj. J. 2004, 20, 267-278.

Detection of ligands for selectins in the oligosaccharide fraction of human milk.

S. Rudloff, C. Stefan, G. Pohlentz, C. Kunz, Eur. J. Nutr. 2002, 41, 85-92.

Expression of glycolipids bearing Lewis phenotypes in tissues and cultured cells of human gynecological cancers.

K. Takehara, K. Kubushiro, K. Kiguchi, I. Ishiwata, K. Tsukazaki, S. Nozawa, M. Iwamori, Jpn. J. Cancer Res. 2002, 93, 1129-1137.


TCIMAIL
Documents
Safety Data Sheet (SDS) Search
Please select Language.

The requested SDS is not available.

• Please check that the Product Number you have entered is correct.

• If your information is correct and you are still not able to view the requested SDS,  please Contact Us for more information.

C of A & Other Certificates
Please enter Lot Number Incorrect Lot Number is entered
Other Documents