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CAS RN: | Product Number: A3251

Anti-6-sulfo LacNAc Monoclonal Antibody (AG105)


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1VIAL
€450.00
1   10  

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*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).


Note:

Product Information
Volume/Quantity : 0.1 mg
Product Form : Purified mouse monoclonal antibody/IgM
Buffer : Phosphate buffered-saline (PBS)
Preparation : The antibody is purified from mouse ascites fluid.
Preservative : 0.05% Sodium azide
Stabilizer : None
Immunogen : Salmonella minnesota strain R595 coated with pure synthetic glycolipid
Specificity : 6-sulfo LacNAc and 6-sulfo Lewis x
Clone Name : AG105

Application
ELISA, Flow cytometry, Immunohistochemistry, Western blot, TLC-immunostaining

Storage
Store at -20 ºC to -80 ºC (Preferably at -80 ºC). It is not recommended storing at 4 ºC. Avoid repeated freezing and thawing.

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Product Number A3251
Physical State (20 deg.C) Liquid
Storage Temperature -80°C
Condition to Avoid Heat Sensitive
Specifications
Appearance Colorless to Almost colorless clear liquid
Titer(ELISA) to pass test
Properties (reference)
GHS
Related Laws:
Transport Information:
HS Number 3002190000
Application
Anti-6-sulfo LacNAc Monoclonal Antibody (AG105)

References

  • Expression of sialyl 6-sulfo Lewis X is inversely correlated with conventional sialyl Lewis X expression in human colorectal cancer.
    • M. Izawa, K. Kumamoto, C. Mitsuoka, A. Kanamori, K. Ohmori, H. Ishida, S. Nakamura, K. Kurata-Miura, K. Sasaki, T Nishi, R Kannagi, Cancer Res. 2000, 60, 1410.
  • 6-Sulfo LacNAc, a novel carbohydrate modification of PSGL-1, defines an inflammatory type of human dendritic cells.
    • K. Schäkel, R. Kannagi, B. Kniep, Y. Goto, C. Mitsuoka, J. Zwirner, A. Soruri, M. von Kietzell, E. P. Rieber, Immunity 2002, 17, 289.
  • TNF-α increases the carbohydrate sulfation of CD44: induction of 6-sulfo N-acetyl lactosamine on N- and O-linked glycans.
  • Expression of N-acetylglucosamine 6-O-sulfotransferases (GlcNAc6STs)-1 and -4 in human monocytes: GlcNAc6ST-1 is implicated in the generation of the 6-sulfo N-acetyllactosamine/Lewis x epitope on CD44 and is induced by TNF-α.
  • Anti-oligosaccharide antibodies as tools for studying sulfated sialoglycoconjugate ligands for siglecs and selectins


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