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CAS RN: 82419-36-1 | Product Number: O0403

Ofloxacin


Purity: >98.0%(T)(HPLC)
Synonyms:
  • 9-Fluoro-3,7-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic Acid
Documents:
5G
€81.00
1   ≥20 
25G
€244.00
1   10  

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Product Number O0403
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__8H__2__0FN__3O__4 = 361.37  
Physical State (20 deg.C) Solid
Condition to Avoid Light Sensitive
CAS RN 82419-36-1
Reaxys Registry Number 3657947
PubChem Substance ID 172089006
Merck Index (14) 6771
MDL Number

MFCD00226105

Specifications
Appearance White to Light yellow powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %
Properties (reference)
Melting Point 263 °C
Maximum Absorption Wavelength 326(H2O) nm
GHS
Related Laws:
RTECS# UU8815500
Transport Information:
HS Number 2941900000
Application
フルオロキノロン系合成抗菌剤,オフロキサシン

Ofloxacin is a synthetic fluoroquinolone antimicrobial structurally related to nalidixic acid [N0490]. Ofloxacin has broad-spectrum bactericidal activity against most Gram-negative bacteria, many Gram-positive bacteria and some anaerobes. The mechanism of action of ofloxacin (and other fluoroquinolone) involves inhibition of bacterial topoisomerase IV and DNA gyrase (topoisomerases II), enzymes required for DNA replication, transcription, repair and recombination. The active S-(-)-enantiomer of ofloxacin is levofloxacin [L0193]. (The product is for research purpose only.)

References


Application
Studies of the Antimicrobial Activity and the Determination of Ofloxacin

References


PubMed Literature


TCIMAIL
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