CAS RN: 57-24-9 | Product Number: S0249
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|Purity / Analysis Method||>98.0%(T)(HPLC)|
|Molecular Formula / Molecular Weight||C__2__1H__2__2N__2O__2 = 334.42|
|Physical State (20 deg.C)||Solid|
|Reaxys Registry Number||52979|
|PubChem Substance ID||87575778|
|SDBS (AIST Spectral DB)||7596|
|Merck Index (14)||8855|
|Appearance||White to Light yellow powder to crystal|
|Purity(HPLC)||min. 98.0 area%|
|Purity(Nonaqueous Titration)||min. 98.0 %|
|Specific rotation [a]20/D||-100 to -108 deg(C=0.25, EtOH)|
|Solubility in Acetic acid||almost transparency|
|Specific Rotation||-108° (C=0.25,EtOH)|
|Solubility in water||Insoluble|
|Degree of solubility in water||160 mg/l 25 °C|
|Solubility (soluble in)||Chloroform|
|Solubility (slightly sol. in)||Acetone|
|Solubility (very slightly)||Methanol,Benzene,Ether,Ethanol|
|Hazard Statements||H300 + H310 : Fatal if swallowed or in contact with skin.
H370 : Causes damage to organs.
H372 : Causes damage to organs through prolonged or repeated exposure.
H410 : Very toxic to aquatic life with long lasting effects.
|Precautionary Statements||P273 : Avoid release to the environment.
P260 : Do not breathe dust/ fume/ gas/ mist/ vapours/ spray.
P262 : Do not get in eyes, on skin, or on clothing.
P280 : Wear protective gloves/ protective clothing.
P391 : Collect spillage.
P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
P302 + P352 + P310 : IF ON SKIN: Wash with plenty of water. Immediately call a POISON CENTER/doctor.
- 1) The strychnine-binding subunit of the glycine receptor shows homology with nicotinic acetylcholine receptors
- 2) Inhibitory glycine receptors: an update (a review)
- 3) Synthesis of Strychnine (a review)
- 4) Is There No End to the Total Syntheses of Strychnine? Lessons Learned in Strategy and Tactics in Total Synthesis
- Voltage clamp study of cat spinal motoneurons during strychnine-induced seizures
- Prevention of strychnine-induced seizures and death by the N-methylated glycine derivatives betaine, dimethylglycine and sarcosine
- Influence of levodopa, apomorphine and 3,4-dihydroxyphenylserine (DOPS) on strychnine-induced seizures in mice
- Glycine potentiates strychnine-induced convulsions: role of NMDA receptors
- Strychnine-induced seizures in mice: the role of noradrenaline
- Effects of MK-801 (dizocilpine) and ketamine on strychnine-induced convulsions in rats: comparison with benzodiazepines and standard anticonvulsants
- H. Kubová, P. Mares, Physiol. Res. 1994, 43, 313.
- L-NAME inhibits pentylenetetrazole and strychnine-induced seizures in mice
- Effect of bis(acetato)tetrakis(imidazole) copper(II) in delaying the onset and reducing the mortality rate of strychnine- and thiosemicarbazide- induced convulsions
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