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CAS RN: 60282-87-3 | Product Number: G0404
Gestodene
 
									 
							Purity: >98.0%(HPLC)(qNMR)
Synonyms:
						
						- 13β-Ethyl-17β-hydroxy-18,19-dinorpregna-4,15-dien-20-yn-3-one
Product Documents:
                    
				
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| Product Number | G0404 | 
| Purity / Analysis Method   | >98.0%(HPLC)(qNMR) | 
| Molecular Formula / Molecular Weight | C__2__1H__2__6O__2 = 310.44 | 
| Physical State (20 deg.C) | Solid | 
| Storage Temperature   | Frozen (<0°C) | 
| Condition to Avoid | Heat Sensitive | 
| Packaging and Container   | 100MG-Glass Bottle with Plastic Insert (View image) | 
| CAS RN | 60282-87-3 | 
| Reaxys Registry Number | 4237181 | 
| PubChem Substance ID | 253659751 | 
| Merck Index (14) | 4413 | 
| MDL Number | MFCD00867858 | 
Specifications
		  | Appearance | White to Almost white powder to crystal | 
| Purity(HPLC) | min. 98.0 area% | 
| Purity(qNMR) | min. 98.0 % | 
| Melting point | 197.0 to 201.0 °C | 
| Specific rotation [a]20/D | -179 to -185 deg(C=0.5,CHCl3) | 
| Solubility in Chloroform | almost transparency | 
| NMR | confirm to structure | 
		Properties (reference)
	| Melting Point | 199 °C | 
| Specific Rotation | -181° (C=0.5,CHCl3) | 
| Maximum Absorption Wavelength | 240 nm (MeOH) | 
 
						 GHS
						 | Pictogram |   | 
| Signal Word | Danger | 
| Hazard Statements | H360 : May damage fertility or the unborn child. | 
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. | 
 
								 Related Laws: 
							   | RTECS# | JF7956000 | 
 
						Transport Information:
							| H.S.code* | 2937.29-000 | 
			Application
		
			Studies on Pharmacology of Gestodene
		
		References
- Comparative pharmacology of newer progestogens
- Gestodene: a review of its pharmacology, efficacy and tolerability in combined contraceptive preparations
- Mechanism-based inhibition of cytochrome P450 3A4 by therapeutic drugs
- Mechanism-based inactivation of human liver microsomal cytochrome P-450 IIIA4 by gestodene
- The estrogenic effects of gestodene, a potent contraceptive progestin, are mediated by its A-ring reduced metabolites
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