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CAS RN: 497-76-7 | 产品编码: A0522
Arbutin
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技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Melting point | 197.0 to 202.0 °C |
| Specific rotation [a]20/D | -63.0 to -68.0 deg(C=4, H2O)(calcd.on anh.substance) |
| Solubility in Water | very faint turbidity |
| Water | max. 3.0 % |
物性（参考值）
| 熔点 | 198 °C |
| 比旋光度 [α]D | -65.5° (C=4,H2O) |
| 水溶性 | 可溶 |
| 溶解性（可溶于） | 醇 |
GHS
相关法规
| RTECS# | CE8863000 |
运输信息
| HS编码* | 2938.90-000 |
应用
Arbutin: A Competitive Inhibitor of Tyrosinase
Arbutin (β-arbutin) is a hydroquinone glycoside, which is accumulated in many plant species such as bearberry (Arctostaphylos uva-ursi L.), bergenia (Bergenia spp.) and myrothamnus (Myrothamnus flabellifolia Welw.). It has been reported that arbutine inhibits the oxidation of L-tyrosine in a competitive manner catalyzed by tyrosinase which is an oxidase that catalyzes the rate-limiting step in melanin (a group of natural pigments) biosynthesis. Arbutins (α- and β-arbutins) are widely used in the cosmetic industry. (Related product: α-arbutin [A3284]) (The product is for research purpose only.)
References
- Arbutin: mechanism of its depigmenting action in human melanocyte culture
- Effects of α- and β-arbutin on activity of tyrosinases from mushroom and mouse melanoma
- Survey and mechanism of skin depigmenting and lightening agents (a review)
- Biotechnological production of arbutins (α- and β-arbutins), skin-lightening agents, and their derivatives (a review)
- Analyses of arbutin and chlorogenic acid, the major phenolic constituents in Oriental pear
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