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CAS RN: 19774-82-4 | 产品编码: A2530
Amiodarone Hydrochloride
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| 产品编码 | A2530 |
纯度/分析方法 
|
>98.0%(T)(HPLC) |
| 分子式/分子量 | C__2__5H__2__9I__2NO__3·HCl = 681.78 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
冷藏 (0-10°C) |
| 应避免的情况 | 光,加热 |
| 包装和容器
|
1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 19774-82-4 |
| 相关CAS RN
|
1951-25-3 |
| Reaxys-RN | 4776323 |
| PubChem物质ID | 172088928 |
| Merck Index (14) | 482 |
| MDL编号 | MFCD00069204 |
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 156 °C(dec.) |
| 最大吸收波长 | 242 nm (MeOH) |
| 水溶性 | 不溶 |
| 在水中的溶解度 | 700 mg/l 25 °C |
| 溶解性（可溶于） | 氯仿, 甲醇 |
| 溶解性（微溶于） | 乙醇 |
| 溶解性（不溶于） | 乙醚 |
GHS
| 象形图 |
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| 信号词 | Warning |
| 危险性说明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. H361 : Suspected of damaging fertility or the unborn child. H362 : May cause harm to breast-fed children. H373 : May cause damage to organs through prolonged or repeated exposure. H413 : May cause long lasting harmful effects to aquatic life. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P263 : Avoid contact during pregnancy/ while nursing. P273 : Avoid release to the environment. P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P405 : Store locked up. |
相关法规
| RTECS# | OB1361000 |
运输信息
| HS编码* | 2932.99-000 |
应用
Amiodarone Hydrochloride: A Vaughan Williams Class III Antiarrhythmic Agent
Amiodarone hydrochloride is a Vaughan Williams class III antiarrhythmic agent. For reference, we also have a synthetic intermediate or a metabolite [B4938] of amiodarone hydrochloride (The product is for research purpose only.)
References
- Effect of amiodarone[2-butyl-3-(3,5-diiodo-4-beta-diethylaminoethoxybenzoyl)benzofuran hydrochloride]
- The adrenergic antagonism of amiodarone
- The effects of amiodarone on the thyroid
- Inhibitory effects of amiodarone and its N-deethylated metabolite on human cytochrome P450 activities: prediction of in vivo drug interactions
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