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CAS RN: 2883-98-9 | 产品编码: A2590
α-Asarone
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| 产品编码 | A2590 |
纯度/分析方法 
|
>98.0%(GC) |
| 分子式/分子量 | C__1__2H__1__6O__3 = 208.26 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
室温 (15°C以下阴凉干燥处) |
| 应避免的情况 | 光 |
| 包装和容器
|
1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 2883-98-9 |
| Reaxys-RN | 1910606 |
| PubChem物质ID | 253659954 |
| MDL编号 | MFCD00064457 |
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 59.0 to 63.0 °C |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 61 °C |
| 沸点 | 298 °C |
| 最大吸收波长 | 312 nm (EtOH) |
| 水溶性 | 不溶 |
| 在水中的溶解度 | 102 mg/l 25 °C |
| 溶解性（可溶于） | 醇, 乙醚 |
GHS
| 象形图 |
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| 信号词 | Warning |
| 危险性说明 | H302 : Harmful if swallowed. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相关法规
| RTECS# | DC2975000 |
运输信息
| HS编码* | 2909.30-900 |
应用
α-Asarone: A Naturally Occurring Phenylpropene with Numerous Pharmacological Activities
α-Asarone (trans-asarone), a naturally occurring phenylpropene, is found in several plants, e.g., Acorus species and Guatteria gaumeriiem Greenman.1,2) α-Asarone is also a component of certain essential oil used in a traditional medicine. It has been reported that α-asarone have numerous pharmacological activities,1,2) including antioxidant3) and neuroprotective4,5) activities. Meanwhile, α-asarone has genotoxic and carcinogenic activities in rodents (liver and small intestine).6) (The product is for research purpose only.)
References
- 1) An overview on traditional uses and pharmacological profile of Acorus calamus Linn. (Sweet flag) and other Acorus species (a review)
- 2) Pharmacology and toxicology of α- and β-Asarone: A review of preclinical evidence (a review)
- 3) Antioxidant property of α-asarone against noise-stress-induced changes in different regions of rat brain
- 4) Protection of cultured rat cortical neurons from excitotoxicity by asarone, a major essential oil component in the rhizomes of Acorus gramineus
- 5) Neuroprotective effect of alpha-asarone on spatial memory and nitric oxide levels in rats injected with amyloid-β(25-35)
- 6) Hepatic Metabolism of Carcinogenic β-Asarone
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