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CAS RN: 179688-53-0 | 产品编码: A2717
6-Acetoxy-7-methoxy-3H-quinazolin-4-one

纯度/分析方法: >98.0%(T)(HPLC)
别名:
- 6-乙酸基-7-甲氧基-3H-喹唑啉-4-酮
- 6-乙酸基-7-甲氧基-4(3H)-喹唑啉酮
- 6-乙酰氧基-7-甲氧基-3,4-二氢喹唑啉-4-酮
- 6-Acetoxy-7-methoxy-4(3H)-quinazolinone
- 6-Acetoxy-7-methoxy-3,4-dihydroquinazolin-4-one
- 6-Acetoxy-7-methoxy-4-hydroxyquinazoline
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技术规格
Appearance | White to Yellow powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Nonaqueous Titration) | min. 98.0 % |
NMR | confirm to structure |
物性(参考值)
熔点 | 297 °C |
GHS
象形图 |
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信号词 | Warning |
危险性说明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
防范说明 | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
相关法规
运输信息
HS编码* | 2933.79-000 |
应用
A Synthetic Intermediate of 4-Anilinoquinazoline Tyrosine Kinase Inhibitors such as Gefitinib
This product has been used as a synthetic intermediate of 4-anilinoquinazoline tyrosine kinase inhibitors such as gefitinib [G0546].
References
- Improved synthesis of substituted 6,7-dihydroxy-4-quinazolineamines: tandutinib, erlotinib and gefitinib
- Synthesis and in vitro antitumor activities of novel 4-anilinoquinazoline derivatives
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