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CAS RN: 20874-52-6 | 产品编码: A3405
Saikosaponin D
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技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Specific rotation | +50.0 to +54.0 deg (C=0.5, Methanol) |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 218 °C |
GHS
相关法规
| RTECS# | VN3099000 |
运输信息
| HS编码* | 2938.90-000 |
应用
Saikosaponin D: An Active Component of Radix Bupleuri
Saikosaponin A [A3408], C [A3189], and D are triterpenoid saponins, and are isolated form Radix Bupleuri which has been used as a traditional medicine for more than 2000 years in Asia countries. It has been reported that they exert diverse biological activities, including anti-inflammatory, antitumor, antiviral, anti-allergic, immunoregulation, and neuroregulation activities mainly through NF-κB, MAPK or other pathways. (The product is for research purpose only.)
References
- Saikosaponin a and its epimer saikosaponin d exhibit anti-inflammatory activity by suppressing activation of NF-κB signaling pathway
- Saikosaponin-d, a novel SERCA inhibitor, induces autophagic cell death in apoptosis-defective cells
- A systematic review of the active saikosaponins and extracts isolated from Radix Bupleuri and their applications
- Evaluation of traditional Chinese herbal medicine: Chaihu (Bupleuri Radix) by both high-performance liquid chromatographic and high-performance thin-layer chromatographic fingerprint and chemometric analysis
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