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CAS RN: 479-98-1 | 产品编码: A3604
Aucubin
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纯度/分析方法: >98.0%(HPLC)
别名：
- 桃叶珊瑚苷
- (2S,3R,4S,5S,6R)-2-[[(1S,4aR,5S,7aS)-5-羟基-7-(羟甲基)-1,4a,5,7a-四氢环戊并[c]吡喃-1-基]氧基]-6-(羟甲基)四氢-2H-吡喃-3,4,5-三醇
- (1S,4aR,5S,7aS)-5-羟基-7-(羟甲基)-1,4a,5,7a-四氢环戊并[c]吡喃-1-基β-D-吡喃葡萄糖苷
- (2S,3R,4S,5S,6R)-2-[[(1S,4aR,5S,7aS)-5-Hydroxy-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-1-yl]oxy]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
- (1S,4aR,5S,7aS)-5-Hydroxy-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-1-yl β-D-Glucopyranoside
产品文档：
| 产品编码 | A3604 |
纯度/分析方法 
|
>98.0%(HPLC) |
| 分子式/分子量 | C__1__5H__2__2O__9 = 346.33 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
冷藏 (0-10°C) |
| 应避免的情况 | 加热 |
| 包装和容器
|
100MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 479-98-1 |
| Reaxys-RN | 50340 |
| MDL编号 | MFCD00136026 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Specific rotation | -160 to -175 deg(C=0.5, water) |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 181 °C |
GHS
相关法规
| RTECS# | LZ5776905 |
运输信息
| HS编码* | 2938.90-000 |
应用
Aucubin: An Iridoid Glycoside with Extensive Biological Effects
Aucubin is an iridoid glycoside commonly found in traditional medicinal herbs such as Aucuba japonica (Garryaceae) and Eucommia ulmoides (Eucommiaceae). Aucubin has been reported to have significant and extensive biological effects, including antioxidant, anti-aging, anti-inflammatory, antifibrotic, anticancer, hepatoprotective, neuroprotective, and osteoprotective properties.1) Aucubin is involved in many signaling pathways and exerts its regulatory effects.2-4) (The product is for research purpose only.)
References
- 1) A review of the pharmacology and toxicology of aucubin
- 2) Aucubin inhibited lipid accumulation and oxidative stress via Nrf2/HO-1 and AMPK signalling pathways
- 3) Aucubin protects chondrocytes against IL-1β-induced apoptosis in vitro and inhibits osteoarthritis in mice model
- 4) Aucubin alleviates oxidative stress and inflammation via Nrf2-mediated signaling activity in experimental traumatic brain injury
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