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CAS RN: 5728-52-9 | 产品编码: B1278
4-Biphenylacetic Acid
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技术规格
| Appearance | White to Orange to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | 161.0 to 165.0 °C |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 163 °C |
GHS
| 象形图 |
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| 信号词 | Danger |
| 危险性说明 | H301 : Toxic if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
相关法规
| RTECS# | DU8229050 |
运输信息
| UN编号 | UN2811 |
| 类别 | 6.1 |
| 包装类别 | III |
| HS编码* | 2916.39-000 |
应用
Felbinac: A Non-Selective Cyclooxygenase (COX) Inhibitor
Felbinac is a nonsteroidal and non-selective cyclooxygenase (COX) inhibitor which has anti-inflammatory effects. The mechanism of action is mainly by inhibition of the enzyme COX in the arachidonic acid metabolism pathway, resulting in reduced prostaglandin synthesis. (The product is for research purpose only.)
References
- Multiple sites of interaction between prostaglandins and non-steroidal anti-inflammatory agents
- The pharmacology of fenbufen, 3-(4-biphenylylcarbonyl)propionic acid, and 4-biphenylacetic acid, interesting antiinflammatory-analgesic agents
- Simultaneous determination of rufloxacin, fenbufen and felbinac in human plasma by high-performance liquid chromatography
- Fluorous derivatization and fluorous-phase separation for fluorometric determination of naproxen and felbinac in human plasma
参考文献
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