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CAS RN: 98437-23-1 | 产品编码: B2893
Benzo[b]thiophene-2-boronic Acid (contains varying amounts of Anhydride)
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| 产品编码 | B2893 |
| 分子式/分子量 | C__8H__7BO__2S = 178.01 |
| 外观与形状（20°C） | 固体 |
储存温度 
|
室温 (15°C以下阴凉干燥处) |
| 包装和容器
|
1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 98437-23-1 |
| Reaxys-RN | 1637924 |
| PubChem物质ID | 87558963 |
| SDBS (AIST Spectral DB) | 51635 |
| MDL编号 | MFCD01075674 |
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(Neutralization titration) | 97.0 to 112.0 % |
物性（参考值）
| 熔点 | 260 °C |
| 溶解性（可溶于） | 四氢呋喃 |
GHS
| 象形图 |
|
| 信号词 | Warning |
| 危险性说明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| 防范说明 | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
相关法规
运输信息
| HS编码* | 2934.99-000 |
应用
AmpC β-lactamase inhibitor
The primary resistance mechanism of microbes to β-lactam antibiotics is hydrolysis of the antibiotics by β-lactamase.1) Benzo[b]thiophene-2-boronic acid is one of boronic acid compounds having β-lactamase (AmpC) inhibition activity (Ki = 0.027 μM).2)
References
- 1) β-Lactamases and β-Lactamase Inhibitors in the 21st Century
- 2) Structure-Based Enhancement of Boronic Acid-Based Inhibitors of AmpC β-Lactamase
PubMed Literature
技术文章
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化学品安全说明书(SDS)
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技术规格
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