Maximum quantity allowed is 999
请选择数量
CAS RN: 20350-15-6 | 产品编码: B3820
Brefeldin A
×
![]()
×
| 产品编码 | B3820 |
纯度/分析方法 
|
>98.0%(HPLC) |
| 分子式/分子量 | C__1__6H__2__4O__4 = 280.36 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
冷冻 (<0°C) |
| 应避免的情况 | 加热 |
| 包装和容器
|
10MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 20350-15-6 |
| Reaxys-RN | 25191 |
| PubChem物质ID | 468590501 |
| Merck Index (14) | 1369 |
| MDL编号 | MFCD12913297 |
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC)(CAD) | min. 98.0 area% |
物性（参考值）
| 熔点 | 204 °C |
| 比旋光度 [α]D | 93° (C=2,MeOH) |
| 最大吸收波长 | 215 nm (EtOH) |
GHS
| 象形图 |
|
| 信号词 | Danger |
| 危险性说明 | H301 : Toxic if swallowed. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
相关法规
| RTECS# | GY8410000 |
运输信息
| UN编号 | UN2811 |
| 类别 | 6.1 |
| 包装类别 | III |
| HS编码* | 2932.20-000 |
应用
Autophagy research / Mitophagy research
References
- Erythroleukemia cells acquire an alternative mitophagy capability
- Discovery of Atg5/Atg7-independent alternative macroautophagy
应用
CRISPR Genome Editing / Research on regenerative medicine
Brefeldin A enhances CRISPR-mediated homology-directed repair (HDR) efficiency.
Reference
- Small molecules enhance CRISPR genome editing in pluripotent stem cells
应用
Brefeldin A: A Macrolide Lactone Antibiotic used as an Inhibitor of Protein Trafficking and Secretion
Brefeldin A (BFA) is a natural fungal macrolide lactone antibiotic. Studies has demonstrated that BFA reversibly interferes with protein trafficking and secretion mediated by the Golgi apparatus and endoplasmic reticulum. Therefore, BFA has been used as a tool to inhibit protein secretion and study the secretory pathway, effects of BFA on Golgi apparatus and other subcellular systems.
References
- Brefeldin A causes disassembly of the Golgi complex and accumulation of secretory proteins in the endoplasmic reticulum
- Brefeldin A: insights into the control of membrane traffic and organelle structure (a review)
- Brefeldin A: deciphering an enigmatic inhibitor of secretion (a review)
产品文档 (部分产品的分析图谱无法提供，敬请谅解。)
化学品安全说明书(SDS)
请选择语言。
如需更多帮助，请联系我 们。
技术规格
CoA及其他文档
请输入批号
批号输入有误。请输入中横线前的4-5个字母数字字符。
示例 CoA
可下载CoA示例。注：该示例不一定是最新批次的CoA。
目前没有该产品的 CoA 示例。
分析图谱
请输入批号
批号输入有误。请输入中横线前的4-5个字母数字字符。
很抱歉，您搜索的分析图谱无法提供。