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CAS RN: 159622-10-3 | 产品编码: B5322
(1R,2S)-1-[(tert-Butoxycarbonyl)amino]-2-vinylcyclopropanecarboxylic Acid
![Chemical Structure of (1R,2S)-1-[(tert-Butoxycarbonyl)amino]-2-vinylcyclopropanecarboxylic Acid](/medias/B5322.jpg?context=bWFzdGVyfHJvb3R8NDI3Njd8aW1hZ2UvanBlZ3xhRFpsTDJnNU1TODRPVEl3TXpneU16QTRNemd5TDBJMU16SXlMbXB3Wnd8MTA2NzI5OWNjNGJmYTdmMDVmN2Q3MDRkNjYxNTZhNmIzN2QwODgxMDliZDM1NWU1OTFkM2NiM2Y3OTdhNjkxYg "(1R,2S)-1-[(tert-Butoxycarbonyl)amino]-2-vinylcyclopropanecarboxylic Acid")
![Thumbnail of (1R,2S)-1-[(tert-Butoxycarbonyl)amino]-2-vinylcyclopropanecarboxylic Acid](/medias/B5322.jpg?context=bWFzdGVyfHJvb3R8MTI4NTV8aW1hZ2UvanBlZ3xhREl4TDJnNVlpODRPVE16TnprMk1UVXhNekkyTDBJMU16SXlMbXB3Wnd8YWNkN2ZmOGY0YjljYjEyZTQwYTU1ZjNkMjE5MDU4ZjA0N2VjNzgxODczN2E0OTFkMzgwNDQ1YWRjYzQxNzhmZQ)
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![(1R,2S)-1-[(tert-Butoxycarbonyl)amino]-2-vinylcyclopropanecarboxylic Acid](/_ui/responsive/theme-tci/images/missing_product_zoom.jpg "(1R,2S)-1-[(tert-Butoxycarbonyl)amino]-2-vinylcyclopropanecarboxylic Acid")
技术规格
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(GC) | min. 98.0 % |
| Purity(Neutralization titration) | min. 96.0 % |
| Specific rotation [a]20/D | +20.0 to +24.0 deg(C=1, MeOH) |
| NMR | confirm to structure |
物性（参考值）
| 比旋光度 [α]D | 22° (C=1,MeOH) |
GHS
相关法规
运输信息
| HS编码* | 2924.29-000 |
应用
A Synthetic Intermediate of Peptidic Protease Inhibitor
This product is used as a synthetic intermediate of peptidic protease inhibitor for the potential treatment of hepatic virus infection, such as BMS-605339.
References
- Development of Related HCV Protease Inhibitors: Macrocyclization of Two Highly Functionalized Dienyl-ureas via Ring-Closing Metathesis
- Discovery and Early Clinical Evaluation of BMS-605339, a Potent and Orally Efficacious Tripeptidic Acylsulfonamide NS3 Protease Inhibitor for the Treatment of Hepatitis C Virus Infection
- P2-Quinazolinones and Bis-Macrocycles as New Templates for Next-Generation Hepatitis C Virus NS3/4a Protease Inhibitors: Discovery of MK-2748 and MK-6325
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技术规格
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