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CAS RN: 73536-69-3 | 产品编码: B6112
Bifendate
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纯度/分析方法: >98.0%(GC)
别名：
- 联苯双酯
- 4,4'-二甲氧基-5,6,5',6'-二(亚甲二氧基)联苯-2,2'-二甲酸二甲酯
- Dimethyl 4,4'-Dimethoxy-5,6,5',6'-di(methylenedioxy)biphenyl-2,2'-dicarboxylate
- 4,4'-Dimethoxy-5,6,5',6'-di(methylenedioxy)biphenyl-2,2'-dicarboxylic Acid Dimethyl Ester
产品文档：
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 179.0 to 183.0 °C |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 181 °C |
| 最大吸收波长 | 276 nm (MeOH) |
GHS
相关法规
| RTECS# | DT4315000 |
运输信息
| HS编码* | 2932.99-000 |
应用
Bifendate (DDB): A Chemical Synthetic Intermediate of a Constituent of Schizandra sp.
Bifendate (dimethyl diphenyl bicarboxylate: DDB) is a chemical synthetic intermediate of schisandrin C, a constituent of Schizandra sp. which have been used in traditional Chinese medicine as a tonic and sedative.1,2) At present, DDB is widely used as a hepatoprotective agent and is recently found to possess immunomodulatory, as well as neurobehavioral potential.2-4) (The product is for research purpose only.)
References
- 1) Bioactivity of neolignans from fructus Schizandrae (a review)
- 2) Differential effect of schisandrin B and dimethyl diphenyl bicarboxylate (DDB) on hepatic mitochondrial glutathione redox status in carbon tetrachloride intoxicated mice
- 3) The effect of dimethyl dimethoxy biphenyl dicarboxylate (DDB) against tamoxifen-induced liver injury in rats: DDB use is curative or protective
- 4) Effect of biphenyl dimethyl dicarboxylate and fluoxetine on performance of normally-fed and protein malnourished psychologically stressed mice in elevated plus maze
- 5)A simple HPLC method for the determination of bifendate: Application to a pharmacokinetic study of bifendate liposome
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