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CAS RN: 1426397-23-0 | 产品编码: C2598
Cefsulodin Sodium Salt Hydrate
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This product has not been tested for potency and is guaranteed for chemical purity.
技术规格
| Appearance | White to Yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(with Total Nitrogen) | min. 95.0 %(calcd.on anh.substance) |
| Specific rotation [a]20/D | +16.0 to +20.0 deg(C=1, H2O)(calcd.on anh.substance) |
| Water | max. 10.0 % |
| NMR | confirm to structure |
物性（参考值）
| 比旋光度 [α]D | 19° (C=1,H2O) |
GHS
| 象形图 |
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| 信号词 | Danger |
| 危险性说明 | H317 : May cause an allergic skin reaction. H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P272 : Contaminated work clothing should not be allowed out of the workplace. P280 : Wear protective gloves. P284 : Wear respiratory protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P342 + P311 : If experiencing respiratory symptoms: Call a POISON CENTER/doctor. P362 + P364 : Take off contaminated clothing and wash it before reuse. P304 + P340 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. |
相关法规
| RTECS# | UU1785000 |
运输信息
| HS编码* | 2941.90-000 |
应用
Cefsulodin Sodium Salt: A Third Generation Cephalosporin Antibiotic with Specific Activity against Pseudomonas Aeruginosa
Cefsulodin sodium salt is a third generation semisynthetic cephalosporin antibiotic, which is chemically synthesized form 7-aminocephalosporanic acid (7-ACA) [A1266]. It has a narrow-spectrum restricted to Pseudomonas aeruginosa. It has no significant activity against other Gram-negative bacteria and very limited activity against Gram-positive bacteria and anaerobic bacteria. It has increased stability to β-lactamases like the other third generation cephalosporin antibiotics.
References
- In vitro antibacterial activity and susceptibility of cefsulodin, an antipseudomonal cephalosporin, to beta-lactamases
- The penetration of antibiotics into aggregates of mucoid and non-mucoid Pseudomonas aeruginosa
- Cross-resistance to meropenem, cephems, and quinolones in Pseudomonas aeruginosa
PubMed Literature
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