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CAS RN: 68401-81-0 | 产品编码: C2622
Ceftizoxime
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This product has not been tested for potency and is guaranteed for chemical purity.
| 产品编码 | C2622 |
纯度/分析方法 
|
>98.0%(T)(HPLC) |
| 分子式/分子量 | C__1__3H__1__3N__5O__5S__2 = 383.40 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
室温 (15°C以下阴凉干燥处) |
| 包装和容器
|
1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 68401-81-0 |
| Reaxys-RN | 5777502 |
| PubChem物质ID | 160870913 |
| Merck Index (14) | 1951 |
| MDL编号 | MFCD00072000 |
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Specific rotation [a]20/D | +135.0 to +145.0 deg(C=1、0.1mol/LNaOH3mL+H2O7mL) |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 227 °C(dec.) |
| 比旋光度 [α]D | 139° (C=1,0.1mol/L NaOH 3mL+H2O 7mL) |
GHS
相关法规
| RTECS# | XI0367375 |
运输信息
| HS编码* | 2941.90-000 |
应用
Ceftizoxime: A Third Generation Semisynthetic Cephalosporin Antibiotic
Ceftizoxime is a third generation semisynthetic cephalosporin antibiotic, which is chemically synthesized form 7-amino-3-nor-3-cephalosporanic acid. It has a broad spectrum of activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria, and is generally more active against Gram-negative bacteria than the first and second generation cephalosporins.
References
- Antibacterial activity of ceftizoxime, a beta-lactamase-stable cephalosporin
- Ceftizoxime. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use
- Ceftizoxime and other third-generation cephalosporins: structure-activity relationships
- Activities of beta-lactam antibiotics against Escherichia coli strains producing extended-spectrum beta-lactamases
- Involvement of MRP4 (ABCC4) in the luminal efflux of ceftizoxime and cefazolin in the kidney
PubMed Literature
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