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CAS RN: 117552-78-0 | 产品编码: C2789
Calcium Dobesilate Hydrate
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| 产品编码 | C2789 |
| 纯度/分析方法 | >98.0%(HPLC) |
| 分子式/分子量 | C__1__2H__1__0CaO__1__0S__2·xH__2O = 418.40 (as Anhydrous) |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 室温 (15°C以下阴凉干燥处) |
| 包装和容器 | 1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 117552-78-0 |
| 相关CAS RN | 20123-80-2 |
| Reaxys-RN | 3639290 |
| PubChem物质ID | 253660116 |
| Merck Index (14) | 3394 |
| MDL编号 | MFCD00867249 |
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Chelometric Titration) | min. 95.0 %(calcd.on anh.substance) |
| Water | 3.0 to 7.0 % |
物性（参考值）
| 水溶性 | 可溶 |
| 溶解性（可溶于） | 醇 |
| 溶解性（不溶于） | 乙醚, 苯, 氯仿 |
GHS
| 象形图 |
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| 信号词 | Warning |
| 危险性说明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| 防范说明 | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
相关法规
| RTECS# | DB6127000 |
运输信息
| HS编码* | 2908.99-000 |
应用
Calcium Dobesilate: An Agent with Reported Antioxidant and Angioprotective Effects
It has been reported that calcium dobesilate possesses antioxidant and angioprotective effects in vitro, but its mechanisms of action are not elucidated. Calcium dobesilate is used in the treatment of diabetic retinopathy. (The product is for research purpose only.)
References
- Angioprotective action of calcium dobesilate against reactive oxygen species-induced capillary permeability in the rat
- Antioxidant properties of calcium dobesilate in ischemic/reperfused diabetic rat retina
- Calcium dobesilate inhibits the alterations in tight junction proteins and leukocyte adhesion to retinal endothelial cells induced by diabetes
- Calcium dobesilate in the treatment of diabetic retinopathy (a review)
- Validation of liquid chromatographic method for analysis of lidocaine hydrochloride, dexamethasone acetate, calcium dobesilate, buthylhydroxyanisol and degradation product hydroquinone in suppositories and ointment
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