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CAS RN: 30299-08-2 | 产品编码: C3100
Clinofibrate
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技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 97.0 % |
| Melting point | 142.0 to 146.0 °C |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 145 °C |
| 水溶性 | 不溶 |
GHS
相关法规
| RTECS# | ES8900000 |
运输信息
| HS编码* | 2918.99-000 |
应用
Clinofibrate: An Inhibitor of 3α-Hydroxysteroid Dehydrogenases (3α-HSD)
Clinofibrate (S-8527) and bezafibrate [B3346] are orally active antihyperlipidemic agents inhibiting human liver 3α-hydroxysteroid dehydrogenases (3α-HSD). They reduce plasma cholesterol levels and show antihyperlipidemic effects in vivo. (The product is for research purpose only.)
References
- Hypolipidemic effect of a new aryloxy compound, S-8527, in experimental animals
- Activation of human liver 3α-hydroxysteroid dehydrogenase by clofibrate derivatives
PubMed Literature
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技术规格
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