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CAS RN: 18472-51-0 | 产品编码: C3105
Chlorhexidine Digluconate (ca. 20% in Water)

技术规格
Appearance | Colorless to Light yellow to Light orange clear liquid |
Concentration(Nonaqueous Titration) | 18.0 to 21.0 w/w% |
物性(参考值)
比重 | 1.07 |
最大吸收波长 | 257 nm (H__2O) |
GHS
象形图 |
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信号词 | Warning |
危险性说明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. H410 : Very toxic to aquatic life with long lasting effects. |
防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P391 : Collect spillage. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
相关法规
RTECS# | DU1950000 |
运输信息
UN编号 | UN3082 |
类别 | 9 |
包装类别 | III |
HS编码* | 2925.29-000 |
应用
Chlorhexidine Digluconate: A Skin Antiseptic and an Inhibitor of Matrix Metalloproteinase (MMP) Activity
Chlorhexidine digluconate, a biguanide, is a skin antiseptic in use in the health care setting with many potential applications for infection control. It is fungicidally active towards a wide range of Gram-positive and Gram-negative bacteria, including MRSA (methicillin-resistant Staphylococcus aureus). Within topical slow release vehicles, chlorhexidine digluconate is used for the treatment of periodontal disease. In addition, chlorhexidine digluconate is an efficient inhibitor of matrix metalloproteinase (MMP) activity. (The product is for research purpose only.)
References
- 1)Cationic antiseptics: diversity of action under a common epithet (a review)
- 2)Community-associated methicillin-resistant Staphylococcus aureus: epidemiology and clinical consequences of an emerging epidemic (a review)
- 3)Chitosan films and hydrogels of chlorhexidine gluconate for oral mucosal delivery
- 4)Chlorhexidine stabilizes the adhesive interface: A 2-year in vitro study
- 5)Inhibition of the activities of matrix metalloproteinases 2, 8, and 9 by chlorhexidine
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