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CAS RN: 6199-67-3 | 产品编码: C3442
Cucurbitacin B
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| 产品编码 | C3442 |
纯度/分析方法 
|
>98.0%(HPLC) |
| 分子式/分子量 | C__3__2H__4__6O__8 = 558.71 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
冷藏 (0-10°C) |
| 应避免的情况 | 加热 |
| 包装和容器
|
25MG-Glass Bottle with Plastic Insert （查看图片）, 5MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 6199-67-3 |
| Reaxys-RN | 2068869 |
| PubChem物质ID | 354335232 |
| Merck Index (14) | 2614 |
| MDL编号 | MFCD07778083 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Water | max. 5.0 % |
物性（参考值）
| 熔点 | 179 °C |
| 最大吸收波长 | 290 nm (EtOH) |
GHS
| 象形图 |
|
| 信号词 | Danger |
| 危险性说明 | H300 : Fatal if swallowed. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
相关法规
| RTECS# | RC6190000 |
运输信息
| UN编号 | UN2811 |
| 类别 | 6.1 |
| 包装类别 | II |
| HS编码* | 2915.39-000 |
应用
Cucurbitacin B: A Triterpenoid Reported as a Promising Antitumor Agent
Cucurbitacin B is a triterpenoid compound isolated from Cucurbitaceae and various plants used as folk medicine in Asian countries, and has recently emerged as a potent antitumor agent. Cucurbitacin B is reported to have anti-proliferation effects on a variety of tumors, and the mechanism of action is still controversial. (The product is for research purpose only.)
References
- Cucurbitacin B markedly inhibits growth and rapidly affects the cytoskeleton in glioblastoma multiforme
- Cucurbitacin B Induces Apoptosis by Inhibition of the JAK/STAT Pathway and Potentiates Antiproliferative Effects of Gemcitabine on Pancreatic Cancer Cells
- Cucurbitacin B induces apoptosis and S phase cell cycle arrest in BEL-7402 human hepatocellular carcinoma cells and is effective via oral administration
- Triterpenoids for cancer prevention and treatment: current status and future prospects (a review)
- A review on the medicinally important plants of the family Cucurbitaceae (a review)
PubMed Literature
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