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CAS RN: 70831-56-0 | 产品编码: C3450
Chicoric Acid
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| 产品编码 | C3450 |
纯度/分析方法 
|
>98.0%(T) |
| 分子式/分子量 | C__2__2H__1__8O__1__2 = 474.37 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
冷藏 (0-10°C) |
| 应避免的情况 | 加热 |
| 包装和容器
|
10MG-Glass Bottle with Plastic Insert （查看图片）, 50MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 70831-56-0 |
| Reaxys-RN | 3229636 |
| PubChem物质ID | 354335030 |
| MDL编号 | MFCD22683653 |
技术规格
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Specific rotation [a]20/D | -360 to -400 deg(C=1, MeOH) |
物性（参考值）
| 熔点 | 206 °C |
| 比旋光度 [α]D | -370° (C=1,MeOH) |
| 最大吸收波长 | 327 nm |
GHS
相关法规
| RTECS# | EJ9852090 |
运输信息
| HS编码* | 2918.29-000 |
应用
Chicoric Acid: A Phenylpropanoid with a Variety of Biological Effects including Anti-HIV Activity
Chicoric acid is a phenylpropanoid found in a number of plants, such as chicory (Cichorium intybus) and Echinacea (Echinacea purpurea), and reportedly has a variety of biological functions, such as antioxidant, anti-inflammatory, antiviral and analgesic activities, and antihyperglycemic effect.1-3) Recently, chicoric acid and its analogs are attracting attention to their anti-HIV activity as HIV-1 integrase inhibitors.4,5) (The product is for research purpose only.)
References
- 1)Chicoric acid is an antioxidant molecule that stimulates AMP kinase pathway in L6 myotubes and extends lifespan in Caenorhabditis elegans
- 2)Effect of Chicoric Acid on Mast Cell-Mediated Allergic Inflammation in Vitro and in Vivo
- 3)Antihyperglycemic effect of a natural chicoric acid extract of chicory (Cichorium intybus L.): a comparative in vitro study with the effects of caffeic and ferulic acids
- 4)Chicoric Acid Analogs as HIV-1 Integrase Inhibitors
- 5)Chicoric acid and its analogues as an anti-HIV integrase agents (a review)
- 6)Pharmacokinetics, tissue distribution, and plasma protein binding study of chicoric acid by HPLC-MS/MS
PubMed Literature
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