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CAS RN: 70356-03-5 | 产品编码: C3478
Cefaclor Monohydrate
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This product has not been tested for potency and is guaranteed for chemical purity.
| 产品编码 | C3478 |
| 纯度/分析方法 | >98.0%(T)(HPLC) |
| 分子式/分子量 | C__1__5H__1__4ClN__3O__4S·H__2O = 385.82 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 冷冻 (<0°C) |
| 应避免的情况 | 光,加热 |
| 包装和容器 | 1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 70356-03-5 |
| PubChem物质ID | 468591117 |
| Merck Index (14) | 1912 |
| MDL编号 | MFCD00071999 |
技术规格
| Appearance | White to Orange to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Specific rotation [a]20/D | +100 to +115 deg(C=0.4, water) |
| Water | 4.5 to 5.5 % |
| NMR | confirm to structure |
物性（参考值）
| 比旋光度 [α]D | 110° (C=0.4,H2O) |
| 水溶性 | 可溶 |
| 溶解性（不溶于） | 苯, 氯仿, 甲醇 |
GHS
| 象形图 |
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| 信号词 | Danger |
| 危险性说明 | H317 : May cause an allergic skin reaction. H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P272 : Contaminated work clothing should not be allowed out of the workplace. P280 : Wear protective gloves. P284 : Wear respiratory protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P342 + P311 : If experiencing respiratory symptoms: Call a POISON CENTER/doctor. P362 + P364 : Take off contaminated clothing and wash it before reuse. P304 + P340 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. |
相关法规
| RTECS# | XI0365000 |
运输信息
| HS编码* | 2941.90-000 |
应用
Cefaclor: A Second Generation Semisynthetic Cephalosporin Antibiotics with 3-Chloro Group
Cefaclor is a second generation semisynthetic cephalosporin antibiotics which possesses a chemical structure substituted with chloro group for the 3-methyl group present in cephalexin [C2248] molecule. Cefaclor is active against a wide range of commonly encountered bacterial pathogens, acting by inhibiting cell wall synthesis. The antibiotic activities against Gram-positive and Gram-negative bacterial pathogens are several times more than that of cephalexin.
References
- Cefaclor: in vitro spectrum of activity and beta-lactamase stability
- Comparison of in vitro activity of cephalexin, cephradine, and cefaclor
- Cefaclor into the millennium (a review)
- Cefaclor revisited (a review)
- Determination of Cefaclor in human plasma by a sensitive and specific liquid chromatographic-tandem mass spectrometric method
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