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CAS RN: 57248-88-1 | 产品编码: D3921
Disodium Pamidronate
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补充产品信息:
Previously this product had been labeled as a hydrate form both in product name and molecular formula. The hydrate form had no exclusive CAS RN and used to share the same CAS RN as the anhydrous form.
To avoid any misleading information and since moisture in product is considered as an impurity, we have decided to remove the term 'Hydrate' from product name and 'xH2O' from the molecular formula for such products.
Please use it at ease since there is no difference in product quality, even if you see the previous indications on a part of label.
| 产品编码 | D3921 |
纯度/分析方法 
|
>95.0%(T) |
| 分子式/分子量 | C__3H__9NNa__2O__7P__2 = 279.03 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
冷藏 (0-10°C) |
| 应避免的情况 | 加热 |
| 包装和容器
|
100MG-Glass Bottle with Plastic Insert （查看图片）, 1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 57248-88-1 |
| 相关CAS RN
|
109552-15-0&40391-99-9 |
| Reaxys-RN | 6459607 |
| PubChem物质ID | 87561576 |
| Merck Index (14) | 7003 |
| MDL编号 | MFCD11045314 |
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(Nonaqueous Titration) | min. 95.0 %(calcd.on anh.substance) |
| Water | max. 25.0 % |
物性（参考值）
GHS
| 象形图 |
|
| 信号词 | Warning |
| 危险性说明 | H302 : Harmful if swallowed. H371 : May cause damage to organs. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P405 : Store locked up. |
相关法规
| RTECS# | SZ6525000 |
运输信息
| HS编码* | 2931.49-900 |
应用
Reviews of pharmacology
References
- Pamidronate: A Review of its Pharmacological Properties and Therapeutic Efficacy in Resorptive Bone Disease
- A. Fitton, D. McTavish, Drugs 1991, 41, 289.
- Structure-Activity Relationships for Inhibition of Farnesyl Diphosphate Synthase in Vitro and Inhibition of Bone Resorption in Vivo by Nitrogen-Containing Bisphosphonates
- J. E. Dunford, K. Thompson, F. P. Coxon, S. P. Luckman, F. M. Hahn, C. D. Poulter, F. H. Ebetino, M. J. Rogers, J Pharmacol. Exp. Ther. 2001, 296, 235.
参考文献
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