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CAS RN: 77883-43-3 | 产品编码: D4126
Doxazosin Mesylate
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| 产品编码 | D4126 |
| 纯度/分析方法 | >98.0%(HPLC)(N) |
| 分子式/分子量 | C__2__3H__2__5N__5O__5·CH__4O__3S = 547.58 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 室温 (15°C以下阴凉干燥处) |
| 包装和容器 | 100MG-Glass Bottle with Plastic Insert （查看图片）, 1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 77883-43-3 |
| 相关CAS RN | 74191-85-8 |
| Reaxys-RN | 7791129 |
| PubChem物质ID | 135727074 |
| MDL编号 | MFCD00216023 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
物性（参考值）
| 熔点 | 269 °C |
GHS
相关法规
| RTECS# | TK8044000 |
运输信息
| HS编码* | 2934.99-000 |
应用
Autophagy research
References
- Doxazosin Attenuates Liver Fibrosis by Inhibiting Autophagy in Hepatic Stellate Cells via Activation of the PI3K/Akt/mTOR Signaling Pathway
- Doxazosin, a Classic Alpha 1-Adrenoceptor Antagonist, Overcomes Osimertinib Resistance in Cancer Cells via the Upregulation of Autophagy as Drug Repurposing
- Mechanisms of Action of Autophagy Modulators Dissected by Quantitative Systems Pharmacology Analysis
应用
Studies of alpha1-Adrenoceptor Antagonists in Cancer Cells
References
- Doxazosin induces apoptosis of benign and malignant prostate cells via a death receptor-mediated pathway
- Anoikis induction by quinazoline based alpha1-adrenoceptor antagonists in prostate cancer cells: antagonistic effect of bcl-2
- Doxazosin inhibits human vascular endothelial cell adhesion, migration, and invasion
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