Product Document Searching Made Easy by 2D Code! | TCI Chemistry News November 2025 | [TCIPracticalExample] The Z-Selective Horner-Wadsworth-Emmons Reaction... | Various analytical charts can be searched on each product detail page and Product Document Search (The kinds of analytical charts differ by product)
Maximum quantity allowed is 999
请选择数量
CAS RN: 117570-53-3 | 产品编码: D5235
Vadimezan
×
![]()
×
| 产品编码 | D5235 |
纯度/分析方法 
|
>98.0%(HPLC) |
| 分子式/分子量 | C__1__7H__1__4O__4 = 282.30 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
冷藏 (0-10°C) |
| 应避免的情况 | 加热 |
| 包装和容器
|
250MG-Glass Bottle with Plastic Insert （查看图片）, 50MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 117570-53-3 |
| Reaxys-RN | 4262852 |
| PubChem物质ID | 468591309 |
| MDL编号 | MFCD00870555 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
物性（参考值）
| 熔点 | 264 °C |
GHS
| 象形图 |
|
| 信号词 | Warning |
| 危险性说明 | H302 : Harmful if swallowed. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相关法规
| RTECS# | ZD5536200 |
运输信息
| HS编码* | 2932.99-000 |
应用
DMXAA: A Compound Used as a Tumor Vascular Disputing Agent and an Immune Adjuvant
DMXAA (other names: vadimezan, ASA404) is a tumor vascular disputing agent (VDA) that can cause a specific and irreversible destruction of established tumor vessels. Reportedly, DMXAA induces apoptosis in tumor vascular endothelium resulting in necrosis at the tumor core. DMXAA showed anti-tumor effects against solid tumors in mouse models but subsequently failed in human clinical trials in 2010.
DMXAA is also a potent type-I interferon (IFN) inducer, and can be used as an adjuvant that targets a specific innate immune signaling pathway. (The product is for research purpose only.)
DMXAA is also a potent type-I interferon (IFN) inducer, and can be used as an adjuvant that targets a specific innate immune signaling pathway. (The product is for research purpose only.)
References
- An overview on Vadimezan (DMXAA): The vascular disrupting agent (a review)
- The chemotherapeutic agent DMXAA as a unique IRF3-dependent type-2 vaccine adjuvant
- Plasma disposition, metabolism and excretion of the experimental antitumour agent 5,6-dimethylxanthenone-4-acetic acid in the mouse, rat and rabbit.
产品文档 (部分产品的分析图谱无法提供，敬请谅解。)
化学品安全说明书(SDS)
请选择语言。
如需更多帮助，请联系我 们。
技术规格
CoA及其他文档
请输入批号
批号输入有误。请输入中横线前的4-5个字母数字字符。
示例 CoA
可下载CoA示例。注：该示例不一定是最新批次的CoA。
目前没有该产品的 CoA 示例。
分析图谱
请输入批号
批号输入有误。请输入中横线前的4-5个字母数字字符。
很抱歉，您搜索的分析图谱无法提供。