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CAS RN: 5928-25-6 | 产品编码: D6144
Decursin
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| 产品编码 | D6144 |
纯度/分析方法 
|
>95.0%(HPLC) |
| 分子式/分子量 | C__1__9H__2__0O__5 = 328.36 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
冷冻 (-20°C) |
| 应避免的情况 | 加热 |
| CAS RN | 5928-25-6 |
| Reaxys-RN | 1626397 |
| MDL编号 | MFCD00272154 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Melting point | 110.0 to 114.0 °C |
| Specific rotation | +138 to +148 deg(C=1, CHCl3) |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 112 °C |
GHS
相关法规
| RTECS# | EM9252405 |
运输信息
| HS编码* | 2932.20-000 |
应用
Decursin: A Phytochemical with Anticancer and Diverse Biological Activities
Decursin is a phytochemical originally isolated from the roots of Angelica gigas Nakai which is a major medicinal herb in Asian countries such as Korea and China.1) Traditionally, its dried root has been used to treat anemia, pain, infections and articular rheumatism. The extract from the herb, decursin, has diverse biological activities. There are reports that decursin is an anti-inflammatory, anticancer, and neuroprotective agent.1-3) Decursin is also a potent protein kinase C (PKC) activator, and induces apoptosis and cell cycle arrest in G1 phase.4,5) (The product is for research purpose only.)
References
- 1) Anti-cancer and other bioactivities of Korean Angelica gigas Nakai (AGN) and its major pyranocoumarin compounds (a review)
- 2) Decursin and decursinol angelate: molecular mechanism and therapeutic potential in inflammatory diseases (a review)
- 3) Neuroprotective and cognitive enhancement potentials of Angelica gigasnakai root: a review
- 4) Decursin: a cytotoxic agent and protein kinase C activator from the root of Angelica gigas
- 5) A novel anticancer agent, decursin, induces G1 arrest and apoptosis in human prostate carcinoma cells
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