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CAS RN: 1239-45-8 | 产品编码: E0370
Ethidium Bromide
×
| 产品编码 | E0370 |
纯度/分析方法 
|
>95.0%(T)(HPLC) |
| 分子式/分子量 | C__2__1H__2__0BrN__3 = 394.32 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
室温 (15°C以下阴凉干燥处) |
| 包装和容器
|
1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 1239-45-8 |
| Reaxys-RN | 3642536 |
| PubChem物质ID | 87569630 |
| SDBS (AIST Spectral DB) | 13171 |
| Merck Index (14) | 4731 |
| MDL编号 | MFCD00011724 |
技术规格
| Appearance | Orange to Brown to Dark purple powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(Argentometric Titration) | min. 95.0 % |
物性（参考值）
GHS
| 象形图 |
|
| 信号词 | Danger |
| 危险性说明 | H330 : Fatal if inhaled. H302 : Harmful if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. H341 : Suspected of causing genetic defects. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P271 : Use only outdoors or in a well-ventilated area. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P284 : Wear respiratory protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor. P403 + P233 : Store in a well-ventilated place. Keep container tightly closed. P405 : Store locked up. |
相关法规
| RTECS# | SF7950000 |
运输信息
| UN编号 | UN1544 |
| 类别 | 6.1 |
| 包装类别 | I |
| HS编码* | 2933.99-000 |
应用
Efflux pump activity assay
Ethidium bromide is used to measure drug efflux activities.1,2)
References
- 1) Phenotype microarray analysis of the drug efflux systems in Salmonella enterica serovar Typhimurium
- 2) Functional cloning and expression of emeA, and characterization of EmeA, a multidrug efflux pump from Enterococcus faecalis
应用
Ethidium Bromide: A Widely Used Dye for DNA and RNA Detection
Ethidium bromide is widely used for DNA and RNA detection. Ethidium bromide binds to double-stranded DNA as an intercalator, inserting itself between the base pairs in the double helix, resulting in changes in the absorption and fluorescence properties of the dye. Ethidium bromide also is used to detect protein–DNA complexes.
References
- A fluorescent complex between ethidium bromide and nucleic acids
- Mechanism of ethidium bromide fluorescence enhancement on binding to nucleic acids
- Mechanism of intercalation into the DNA double helix by ethidium
- Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations
- Rapid and sensitive ethidium bromide fluorescence quenching assay of polyamine conjugate-DNA interactions for the analysis of lipoplex formation in gene therapy
- Stability and structural features of DNA intercalation with ethidium bromide, acridine orange and methylene blue
PubMed Literature
技术文章
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化学品安全说明书(SDS)
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技术规格
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其他文件
相关产品
![Ethidium Bromide (0.5mg/mL in Water) (in Dropper Bottle) [for Electrophoresis]](/medias/E1363.jpg?context=bWFzdGVyfHJvb3R8MzU3NTd8aW1hZ2UvanBlZ3xhRFZtTDJnek9DODRPVE13TlRnNU1UUTNNVFkyTDBVeE16WXpMbXB3Wnd8OTNjYzQxMjUyYmI0MWNiMGZiZWM4YWM0MTY3ODFkNjkyZjRmYjY3ZDE0Yjk5YjM3YzQyM2U5MDMyZmRiMzMwMA "Ethidium Bromide (0.5mg/mL in Water) (in Dropper Bottle) [for Electrophoresis]")
Ethidium Bromide (0.5mg/mL in Water) (in Dropper Bottle) [for Electrophoresis]
| 产品 | E1363 |
| CAS RN | 1239-45-8 |
| 纯度/分析方法 |