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CAS RN: 100501-62-0 | 产品编码: E0888
Ethyl 1-Ethyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylate

技术规格
Appearance | White to Almost white powder to crystal |
Purity(GC) | min. 98.0 % |
Melting point | 205.0 to 209.0 °C |
NMR | confirm to structure |
物性(参考值)
熔点 | 207 °C |
GHS
象形图 |
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信号词 | Warning |
危险性说明 | H317 : May cause an allergic skin reaction. H412 : Harmful to aquatic life with long lasting effects. |
防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P273 : Avoid release to the environment. P272 : Contaminated work clothing should not be allowed out of the workplace. P280 : Wear protective gloves. P302 + P352 : IF ON SKIN: Wash with plenty of water. P362 + P364 : Take off contaminated clothing and wash it before reuse. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. |
相关法规
运输信息
HS编码* | 2933.99-000 |
应用
A Synthetic Intermediate of Fluoroquinolone Antibiotics
This product has been used as a synthetic intermediate of fluoroquinolone antibiotics, including lomefloxacin hydrochloride [L0216].
References
- Synthesis and in vitro antimicrobial evaluation of novel fluoroquinolone derivatives
- Synthesis and antibacterial evaluation of novel 8-fluoro Norfloxacin derivatives as potential probes for methicillin and vancomycin-resistant Staphylococcus aureus
- Thermochemical reaction of 7-azido-1-ethyl-6,8-difluoroquinolone-3-carboxylate with heterocyclic amines. An expeditious synthesis of novel fluoroquinolone derivatives
应用
Synthesis of Antibacterial Agents
References
- Hybrid Antibacterials. DNA Polymerase-Topoisomerase Inhibitors
- Pyridonecarboxylic acids antibacterial agents. 11. Intramolecular cyclization of 7-substituted 6-fluoro-1,8-naphthyridine and -quinoline derivatives
- Synthesis and antibacterial evaluation of novel 8-fluoro Norfloxacin derivatives as potential probes for methicillin and vancomycin-resistant Staphylococcus aureus
参考文献
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技术规格
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