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CAS RN: 42017-89-0 | 产品编码: F1011
Fenofibric Acid
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| 产品编码 | F1011 |
纯度/分析方法 
|
>98.0%(GC)(T) |
| 分子式/分子量 | C__1__7H__1__5ClO__4 = 318.75 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
室温 (15°C以下阴凉干燥处) |
| 包装和容器
|
1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 42017-89-0 |
| Reaxys-RN | 2058973 |
| PubChem物质ID | 253661146 |
| MDL编号 | MFCD00792461 |
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | 179.0 to 183.0 °C |
物性（参考值）
| 熔点 | 181 °C |
GHS
| 象形图 |
|
| 信号词 | Warning |
| 危险性说明 | H302 : Harmful if swallowed. H411 : Toxic to aquatic life with long lasting effects. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P391 : Collect spillage. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
相关法规
| RTECS# | UA2453000 |
运输信息
| UN编号 | UN3077 |
| 类别 | 9 |
| 包装类别 | III |
| HS编码* | 2918.30-000 |
应用
Fenofibric Acid: An Activator of peroxisome proliferator activated receptor α(PPARα)
Fenofibric acid, an active form of fenofibrate [F0674], activates peroxisome proliferator activated receptor α (PPARα) to modify fatty acid and lipid metabolite. Therefore, fenofibric acid helps reduce lowering triglycerides (TG) and high-density lipoprotein cholesterol (HDL-C) levels, and increase low-density lipoprotein cholesterol (LDL-C) level in the blood. Fenofibric acid and fenofibrate are often co-administered with a HMG-CoA reductase inhibitor (statin) to the treatment of dyslipidemia. (The product is for research purpose only.)
References
- Fenofibric Acid, an Active Form of Fenofibrate, Increases Apolipoprotein A-I-Mediated High-Density Lipoprotein Biogenesis by Enhancing Transcription of ATP-Binding Cassette Transporter A1 Gene in a Liver X Receptor-Dependent Manner
- Fenofibric acid: In combination therapy in the treatment of mixed dyslipidemia (a review)
- Determination of bezafibrate, ciprofibrate and fenofibric acid in human plasma by high-performance liquid chromatography
- Stability indicating UPLC method for simultaneous determination of atorvastatin, fenofibrate and their degradation products in tablets
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