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CAS RN: 1195-08-0 | 产品编码: F1322
5-Formyluracil
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| 产品编码 | F1322 |
| 纯度/分析方法 | >98.0%(T)(HPLC) |
| 分子式/分子量 | C__5H__4N__2O__3 = 140.10 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 室温 (15°C以下阴凉干燥处) |
| 储存在惰性气体下 | 存放于惰性气体之中 |
| 应避免的情况 | 空气 |
| 包装和容器 | 1G-Glass Bottle with Plastic Insert （查看图片）, 200MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 1195-08-0 |
| Reaxys-RN | 125791 |
| MDL编号 | MFCD00192185 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Volumetric Analysis) | min. 98.0 % |
| NMR | confirm to structure |
物性（参考值）
GHS
相关法规
| RTECS# | UV7700120 |
运输信息
| HS编码* | 2933.59-000 |
应用
5-Formyluracil: A Major Oxidation Product of Thymine in DNA, and an Epigenetic Modification of Cytosine and Thymine
5-Formyluracil is a major oxidation product of thymine in DNA, and an epigenetic modification of cytosine and thymine. Recently, it has been reported that the level of 5-formyluracil is higher in certain cancer tissues than in normal tissues adjacent to the tumor. Therefore, the detection of 5-formyluracil as a biomarker has attracted widespread attention.
References
- Cellular effects of 5-formyluracil in DNA (a review)
- Chemoselective labeling and site-specific mapping of 5-formylcytosine as a cellular nucleic acid modification (a review)
- Detection and Application of 5-Formylcytosine and 5-Formyluracil in DNA (a review)
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