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CAS RN: 59870-68-7 | 产品编码: G0534
Glabridin
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纯度/分析方法: >98.0%(GC)
别名：
- 光甘草定
- (R)-4-(3,4-二氢-8,8-二甲基-2H,8H-苯并[1,2-b:3,4-b']二吡喃-3-基)-1,3-苯二酚
- 4-[(3R)-8,8-二甲基-3,4-二氢-2H,8H-吡喃并[2,3-f]苯并吡喃-3-基]-1,3-苯二酚
- (R)-4-(8,8-二甲基-3,4-二氢-2H,8H-吡喃并[2,3-f]苯并吡喃-3-基)苯-1,3-二酚
- (R)-4-(3,4-Dihydro-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b']dipyran-3-yl)-1,3-benzenediol
- 4-[(3R)-8,8-Dimethyl-3,4-dihydro-2H,8H-pyrano[2,3-f]chromen-3-yl]-1,3-benzenediol
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产品文档：
| 产品编码 | G0534 |
纯度/分析方法 
|
>98.0%(GC) |
| 分子式/分子量 | C__2__0H__2__0O__4 = 324.38 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
冷冻 (<0°C) |
| 应避免的情况 | 加热 |
| 包装和容器
|
1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 59870-68-7 |
| Reaxys-RN | 7141956 |
| MDL编号 | MFCD03427694 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 228.0 to 232.0 °C |
| Specific rotation | +8.5 to +10.5 deg(C=0.5, methanol) |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 230 °C |
| 溶解性（可溶于） | 乙醇 |
GHS
相关法规
| RTECS# | CZ8937649 |
运输信息
| HS编码* | 2932.99-000 |
应用
Paraptosis research / Paraptosis like cell death
Reference
- Glabridin induces paraptosis-like cell death via ER stress in breast cancer cells
- Phytochemistry and biological properties of glabridin (a review)
- Pharmacological properties of glabridin (a flavonoid extracted from licorice): A comprehensive review
- Review on the Diverse Biological Effects of Glabridin
- Simultaneous extraction and separation of liquiritin, glycyrrhizic acid, and glabridin from licorice root with analytical and preparative chromatography
- Rapid RP-HPLC Method for the Quantification of Glabridin in Crude Drug and in Polyherbal Formulation
应用
Glabridin: A Prenylated Isoflavonoid with Various Biological Properties
Glabridin is a prenylated isoflavonoid specifically found in the roots of licorice (Glycyrrhiza glabra L.), and has various biological properties such as antioxidant, anti-inflammatory, anti-tumor, anti-microorganism, anti-atherogenic, energy metabolism regulator, estrogenic, neuroprotective, anti-osteoporotic, skin whitening, and GABAergic inhibition. In addition, many signaling pathways, including NF-κB, MAPK, Wnt/β-catenin, ERα/SRC-1, PI3K/AKT, and AMPK, have been implicated in the regulatory activities of glabridin. (The product is for research purpose only.)
References
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技术规格
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