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CAS RN: 465-99-6 | 产品编码: H1645
Hederagenin
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| 产品编码 | H1645 |
纯度/分析方法 
|
>98.0%(T)(HPLC) |
| 分子式/分子量 | C__3__0H__4__8O__4 = 472.71 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
冷藏 (0-10°C) |
| 应避免的情况 | 加热 |
| 包装和容器
|
200MG-Glass Bottle with Plastic Insert （查看图片）, 50MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 465-99-6 |
| Reaxys-RN | 2711855 |
| PubChem物质ID | 354335220 |
| Merck Index (14) | 4624 |
| MDL编号 | MFCD00017385 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Specific rotation [a]20/D | +81.0 to +85.0 deg(C=1, Pyridine) |
物性（参考值）
| 熔点 | 334 °C |
| 最大吸收波长 | 405 nm (H__2SO__4) |
GHS
相关法规
运输信息
| HS编码* | 2918.19-000 |
应用
Hederagenin: A Pentacyclic Triterpenoid with Many Biological Activities
Hederagenin is a pentacyclic triterpenoid. It is the aglycone part of numerous saponins found in Hedera helix, etc. and found in a variety of traditional medicines and food products. Reportedly, hederagenin and its glycosides (saponins) possess many biological activities such as anti-inflammatory1,2), antitumor3,4), antimutagenic5) and anticomplementary6) activities. Furthermore, hederagenin has been reported as a serotonin, norepinephrine and dopamine reuptake inhibitor.7) (The product is for research purpose only.)
References
- 1)Anti-inflammatory activities of hederagenin and crude saponin isolated from Sapindus mukorossi Gaertn
- 2)In vitro antiinflammatory activity of kalopanaxsaponin A isolated from Kalopanax pictus in murine macrophage RAW 264.7 cells
- 3)Hederagenin as a triterpene template for the development of new antitumor compounds
- 4)Kalopanaxsaponin A is a basic saponin structure for the anti-tumor activity of hederagenin monodesmosides
- 5)Essential moiety for antimutagenic and cytotoxic activity of hederagenin monodesmosides and bisdesmosides isolated from the stem bark of Kalopanax pictus
- 6)In vitro anticomplementary activity of hederagenin saponins isolated from roots of Dipsacus asper
- 7)The extracts of Fructus Akebiae, a preparation containing 90% of the active ingredient hederagenin: Serotonin, norepinephrine and dopamine reuptake inhibitor
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