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CAS RN: 148849-67-6 | 产品编码: I0847
Ivabradine Hydrochloride
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| 产品编码 | I0847 |
纯度/分析方法 
|
>98.0%(HPLC)(N) |
| 分子式/分子量 | C__2__7H__3__6N__2O__5·HCl = 505.05 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
冷藏 (0-10°C) |
| 应避免的情况 | 加热 |
| 包装和容器
|
1G-Glass Bottle with Plastic Insert （查看图片）, 200MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 148849-67-6 |
| 相关CAS RN
|
155974-00-8 |
| Reaxys-RN | 9681567 |
| PubChem物质ID | 253659556 |
| Merck Index (14) | 5247 |
| MDL编号 | MFCD00929899 |
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
| Purity(Argentometric Titration) | min. 97.0 % |
| Specific rotation [a]20/D | +6.0 to +8.5 deg(C=1, DMSO) |
物性（参考值）
| 熔点 | 140 °C |
| 比旋光度 [α]D | 7° (C=1,DMSO) |
GHS
相关法规
运输信息
| HS编码* | 2933.79-000 |
应用
Studies of the Selective If Current Inhibitor Ivabradine
References
- Current-dependent block of rabbit sino-atrial node If channels by ivabradine
- Electrophysiological effects of S 16257, a novel sino-atrial node modulator, on rabbit and guinea pig cardiac preparations: comparison with UL-FS 49
- Coronary and hemodynamic effects of S 16257, a new bradycardic agent, in resting and exercising conscious dogs
- L. Simon, B. Ghaleh, L. Puybasset, J. F. Giudicelli, A. Berdeaux, J. Pharmacol. Exp. Ther. 1995, 275, 659.
- Mode of action of bradycardic agent, S 16257, on ionic currents of rabbit sinoatrial node cells
- Heart rate lowering by specific and selective If current inhibition with ivabradine. A new therapeutic perspective in cardiovascular disease
PubMed Literature
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