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CAS RN: 52659-56-0 | 产品编码: K0059
Kirenol
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| 产品编码 | K0059 |
纯度/分析方法 
|
>98.0%(GC) |
| 分子式/分子量 | C__2__0H__3__4O__4 = 338.49 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
冷藏 (0-10°C) |
| 应避免的情况 | 加热 |
| 包装和容器
|
25MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 52659-56-0 |
| Reaxys-RN | 2336586 |
| PubChem物质ID | 354335399 |
| MDL编号 | MFCD00210519 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Specific rotation [a]20/D | -29.0 to -32.0 deg(C=0.5, pyridine) |
| Purity(GC) | min. 98.0 % |
| Melting point | 197.0 to 201.0 °C |
物性（参考值）
| 熔点 | 199 °C |
| 比旋光度 [α]D | -30° (C=0.5,Pyridine) |
GHS
相关法规
| RTECS# | SF7352310 |
运输信息
| HS编码* | 2906.19-000 |
应用
Kirenol: A Natural Diterpenoid with Versatile Biological Activities
Kirenol is a biologically active diterpenoid isolated from Herba Siegesbeckiae. Recent studies have revealed that kirenol exhibits a variety of biological activities containing anti-oxidant, anti-inflammatory, anti-allergic, and anti-arthritic effects. (The product is for research purpose only.)
References
- Kirenol upregulates nuclear Annexin-1 which interacts with NF-κB to attenuate synovial inflammation of collagen-induced arthritis in rats
- Kirenol exerts a potent anti-arthritic effect in collagen-induced arthritis by modifying the T cells balance
- Kirenol inhibits adipogenesis through activation of the Wnt/β-catenin signaling pathway in 3T3-L1 adipocytes
- A rapid and simple RP-HPLC method for quantification of kirenol in rat plasma after oral administration and its application to pharmacokinetic study
参考文献
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