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CAS RN: 5989-27-5 | 产品编码: L0047
(+)-Limonene
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Synonym: d-Limonene
技术规格
| Appearance | Colorless to Almost colorless clear liquid |
| Purity(GC) | min. 95.0 % |
| Optical purity(GC) | min. 98.0 ee% |
物性（参考值）
| 熔点 | -75 °C |
| 沸点 | 176 °C |
| 闪点 | 51 °C |
| 比重 | 0.84 |
| 比旋光度 [α]D | 113° (C=10,EtOH) |
| 折射率 | 1.47 |
| 水溶性 | 不溶 |
| 在水中的溶解度 | 13.8 mg/l 25 °C |
| 溶解性（可与之混溶） | 乙醚, 醇 |
GHS
| 象形图 |
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| 信号词 | Danger |
| 危险性说明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. H317 : May cause an allergic skin reaction. H304 : May be fatal if swallowed and enters airways. H410 : Very toxic to aquatic life with long lasting effects. H226 : Flammable liquid and vapor. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P273 : Avoid release to the environment. P272 : Contaminated work clothing should not be allowed out of the workplace. P240 : Ground/bond container and receiving equipment. P210 : Keep away from heat/sparks/open flames/hot surfaces. No smoking. P233 : Keep container tightly closed. P243 : Take precautionary measures against static discharge. P241 : Use explosion-proof electrical/ ventilating/ lighting/ equipment. P242 : Use only non-sparking tools. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P370 + P378 : In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish. P391 : Collect spillage. P331 : Do NOT induce vomiting. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P303 + P361 + P353 : IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. P301 + P310 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. P403 + P235 : Store in a well-ventilated place. Keep cool. P405 : Store locked up. |
相关法规
| RTECS# | GW6360000 |
运输信息
| UN编号 | UN2319 |
| 类别 | 3 |
| 包装类别 | III |
| HS编码* | 2902.19-000 |
应用
(+)-Limonene: A Monocyclic Monoterpene with Anticancer, Anti-Microbial and Anti-Inflammatory Activities.
(+)-Limonene is a monocyclic monoterpene that has been found in various plant oil citrus fruit peel as the fragrance of oranges. It is the D-isomer or (R)-enantiomer of (±)-limonene [L0046]. It is used as a flavoring compound, and has been reported to have diverse biological activities, including anticancer,1,2) anti-microbial3) and anti-inflammatory4) activities. Other related products: (+)-Limonene [L0105], (-)-Limonene [L0132]. (The product is for research purpose only.)
References
- 1) Chemoprevention and therapy of cancer by d-limonene (a review)
- 2) d-Limonene: an emerging antineoplastic agent (a review)
- 3) Antimicrobial activity of limonene enantiomers and 1,8-cineole alone and in combination
- 4) d-limonene suppresses doxorubicin-induced oxidative stress and inflammation via repression of COX-2, iNOS, and NFκB in kidneys of Wistar rats
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