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CAS RN: 545-47-1 | 产品编码: L0321
Lupeol
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| 产品编码 | L0321 |
| 纯度/分析方法 | >97.0%(HPLC) |
| 分子式/分子量 | C__3__0H__5__0O = 426.73 |
| 外观与形状（20°C） | 固体 |
| 储存温度 | 冷藏 (0-10°C) |
| 应避免的情况 | 加热 |
| 包装和容器 | 100MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 545-47-1 |
| Reaxys-RN | 2063497 |
| PubChem物质ID | 468592149 |
| Merck Index (14) | 5608 |
| MDL编号 | MFCD00017351 |
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC)(CAD) | min. 97.0 area% |
| Specific rotation | +27.0 to +29.0 deg (C=0.5, CHCl3) |
| NMR | confirm to structure |
| Melting point | 208.0 to 212.0 °C |
物性（参考值）
| 熔点 | 210 °C |
| 最大吸收波长 | 350 nm (CHCl__3) |
| 溶解性（可溶于） | 乙醚, 苯 |
GHS
相关法规
| RTECS# | OK5763000 |
运输信息
| HS编码* | 2906.19-000 |
应用
Lupeol: an anti-inflammatory triterpen targeting key signaling pathways
Lupeol is a pentacyclic triterpen contained in vegetable oils, cereals, fruits and vegetables. It has been reported that lupeol has potent anti-inflammatory, anti-carcinogenic, anti-mutagenic, and anti-malarial activity.1) Many studies on the mechanisms of action suggest that lupeol is a multi-target agent with immense anti-inflammatory potential targeting key signaling pathways which involve nuclear factor kappa B (NF-κB), cFLIP, Fas, Kras, phosphatidylinositol-3-kinase (PI3K)/Akt and Wnt/β-catenin in a variety of cells.2-4) (The product is for research purpose only.)
References
- 1) Lupeol: Connotations for chemoprevention (a review)
- 2) Lupeol modulates NF-κB and PI3K/Akt pathways and inhibits skin cancer in CD-1 mice
- 3) Lupeol, a novel anti-inflammatory and anti-cancer dietary triterpene (a review)
- 4) Beneficial health effects of lupeol triterpene: A review of preclinical studies (a review)
- 5) Separation and identification of some common isomeric plant triterpenoids by thin-layer chromatography and high-performance liquid chromatography
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