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CAS RN: 15622-65-8 | 产品编码: M2252
Molindone Hydrochloride
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纯度/分析方法: >98.0%(T)(HPLC)
别名：
- 盐酸吗啉吲酮
- 3-乙基-6,7-二氢-2-甲基-5-(吗啉代甲基)-1H-吲哚-4(5H)-酮盐酸盐
- 3-乙基-1,5,6,7-四氢-2-甲基-5-(4-吗啉基甲基)-4H-吲哚-4-酮盐酸盐
- 3-Ethyl-6,7-dihydro-2-methyl-5-(morpholinomethyl)-1H-indol-4(5H)-one Hydrochloride
- 3-Ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-4H-indol-4-one Hydrochloride
产品文档：
技术规格
| Appearance | White to Yellow to Orange powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| NMR | confirm to structure |
物性（参考值）
GHS
| 象形图 |
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| 信号词 | Danger |
| 危险性说明 | H301 : Toxic if swallowed. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
相关法规
| RTECS# | NM3325000 |
运输信息
| UN编号 | UN2811 |
| 类别 | 6.1 |
| 包装类别 | III |
| HS编码* | 2934.99-000 |
应用
Molindone Hydrochloride: A Dihydroindolone Neuroleptic with Dopamine Receptors Antagonist Activity
Molindone hydrochloride is a dihydroindolone neuroleptic with dopamine receptors antagonist activity. However, it is reported that molindone has much lower affinity for D2 receptors than most antipsychotic agents and has a low affinity for D1 receptors. (The product is for research purpose only.)
References
- Preformulation studies. I. Molindone hydrochloride
- Dopaminergic neurons: an in vivo system for measuring drug interactions with presynaptic receptors
- Neuroleptic-induced catalepsy: a D2 blockade phenomenon?
- Molindone (a review)
- Determination of molindone enantiomers in human plasma by high-performance liquid chromatography-tandem mass spectrometry using macrocyclic antibiotic chiral stationary phases
参考文献
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技术规格
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