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CAS RN: 13614-98-7 | 产品编码: M2288
Minocycline Hydrochloride
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| 产品编码 | M2288 |
纯度/分析方法 
|
>98.0%(T)(HPLC) |
| 分子式/分子量 | C__2__3H__2__7N__3O__7·HCl = 493.94 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
冷藏 (0-10°C) |
| 应避免的情况 | 加热 |
| 包装和容器
|
1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 13614-98-7 |
| 相关CAS RN
|
10118-90-8 |
| Reaxys-RN | 4836328 |
| PubChem物质ID | 160871228 |
| Merck Index (14) | 6202 |
| MDL编号 | MFCD00083669 |
技术规格
| Appearance | Light yellow to Yellow to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 %(calcd.on anh.substance) |
| Specific rotation [a]20/D | -170 to -180 deg(C=0.5、0.1mol/L HCl) |
| Water | 4.3 to 8.0 % |
物性（参考值）
| 比旋光度 [α]D | -175° (C=0.5,0.1mL/L HCl) |
| 水溶性 | 微溶 |
| 溶解性（可溶于） | 甲醇, 二甲基甲酰胺 |
GHS
| 象形图 |
|
| 信号词 | Danger |
| 危险性说明 | H360 : May damage fertility or the unborn child. H362 : May cause harm to breast-fed children. H317 : May cause an allergic skin reaction. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P263 : Avoid contact during pregnancy/ while nursing. P272 : Contaminated work clothing should not be allowed out of the workplace. P260 : Do not breathe dusts or mists. P270 : Do not eat, drink or smoke when using this product. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P362 + P364 : Take off contaminated clothing and wash it before reuse. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. P405 : Store locked up. |
相关法规
| RTECS# | QI7630500 |
运输信息
| HS编码* | 2941.30-000 |
应用
Studies on Antibiotic Activity
References
- The broad-spectrum activity and efficacy of catheters coated with minocycline and rifampin
- Neuroprotective and anti-human immunodeficiency virus activity of minocycline
应用
Neuroprotective Studies
References
- Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice
- Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease
- A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window
- Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease
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