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CAS RN: 53-36-1 | 产品编码: M2635
Methylprednisolone Acetate
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| 产品编码 | M2635 |
纯度/分析方法 
|
>98.0%(HPLC) |
| 分子式/分子量 | C__2__4H__3__2O__6 = 416.51 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
冷藏 (0-10°C) |
| 应避免的情况 | 加热 |
| 包装和容器
|
1G-Glass Bottle with Plastic Insert （查看图片）, 250MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 53-36-1 |
| Reaxys-RN | 3176535 |
| PubChem物质ID | 468592211 |
| MDL编号 | MFCD00200356 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Specific rotation [a]20/D | +95.0 to +100.0 deg(C=1, CHCl3) |
| NMR | confirm to structure |
物性（参考值）
| 最大吸收波长 | 243 nm (EtOH) |
GHS
| 象形图 |
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| 信号词 | Warning |
| 危险性说明 | H361 : Suspected of damaging fertility or the unborn child. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
相关法规
| RTECS# | TU4154050 |
运输信息
| HS编码* | 2937.29-000 |
应用
Methylprednisolone Acetate: A Prodrug of 6α-Methylprednisolone
Methylprednisolone acetate is the acetate ester of a synthetic glucocorticoid receptor agonist, 6α-methylprednisolone [M1665], with immunosuppressive and anti-inflammatory effects. Methylprednisolone acetate is converted into the active metabolite 6α-methylprednisolone in the body, which activates glucocorticoid receptor mediated gene expression. (The product is for research purpose only.)
References
- Effects of pulse methylprednisolone on bone and marrow tissues: corticosteroid-induced osteonecrosis in rabbits
- Pharmacokinetics of methylprednisolone acetate after intra-articular administration and its effect on endogenous hydrocortisone and cortisone secretion in horses
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