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CAS RN: 19457-55-7 | 产品编码: M3121
6-Methyleneandrost-4-ene-3,17-dione
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| 产品编码 | M3121 |
纯度/分析方法 
|
>98.0%(HPLC) |
| 分子式/分子量 | C__2__0H__2__6O__2 = 298.43 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
室温 (15°C以下阴凉干燥处) |
| 包装和容器
|
1G-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 19457-55-7 |
| Reaxys-RN | 4514172 |
| PubChem物质ID | 354335792 |
| MDL编号 | MFCD09038727 |
技术规格
| Appearance | White to Orange to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Specific rotation [a]20/D | +390 to +430 deg(C=1, CHCL3) |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 164 °C(dec.) |
| 比旋光度 [α]D | 411° (C=1,CHCl3) |
| 最大吸收波长 | 259 nm (EtOH) |
GHS
| 象形图 |
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| 信号词 | Warning |
| 危险性说明 | H361 : Suspected of damaging fertility or the unborn child. |
| 防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
相关法规
运输信息
| HS编码* | 2937.90-000 |
应用
A Synthetic Intermediate of Exemestane
This product is a synthetic intermediate of exemestane (FCE 24304) [E0941] which is a potent and selective aromatase inhibitor.
References
- 6-Methylenandrosta-1,4-diene-3,17-dione (FCE 24304): a new irreversible aromatase inhibitor
- Synthesis and aromatase inhibition by potential metabolites of exemestane (6-methylenandrosta-1,4-diene-3,17-dione)
- 1,2-Dehydrogenation of steroidal 6-methylene derivatives. Synthesis of exemestane
- Development and validation of a stability indicating LC method for the assay and related substances determination of Exemestane, an aromatase inhibitor
参考文献