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CAS RN: 159857-80-4 | 产品编码: M3224
MC-Val-Cit-PAB-OH
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纯度/分析方法: >98.0%(HPLC)(N)
别名：
- MC-Val-Cit-PAB-OH
- N-[6-(2,5-二氧代-2,5-二氢-1H-吡咯-1-基)己酰基]-L-缬氨酰-N5-(氨基甲酰基)-[4-(羟基甲基)苯基]-L-鸟氨酰胺
- 6-(2,5-二氧代-2,5-二氢-1H-吡咯-1-基)-N-[(S)-1-[[(S)-1-[[4-(羟甲基)苯基]氨基]-1-氧代-5-脲基戊烷-2-基]氨基]-3-甲基-1-氧代丁烷-2-基]己酰胺
- N-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]-L-valyl-N5-carbamoyl-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide
- 6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-[(S)-1-[[(S)-1-[[4-(hydroxymethyl)phenyl]amino]-1-oxo-5-ureidopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]hexanamide
产品文档：
技术规格
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
物性（参考值）
GHS
相关法规
运输信息
| HS编码* | 2925.19-000 |
应用
A Peptide Linker Designed for Antibody-Drug Conjugate (ADC)
This product is a peptide linker designed for Antibody-Drug Conjugate (ADC) which concept is to use an antibody to deliver a cytotoxic drug (payload) selectively to a target such as a tumor-associated antigen.
References
- Cathepsin B-Labile Dipeptide Linkers for Lysosomal Release of Doxorubicin from Internalizing Immunoconjugates: Model Studies of Enzymatic Drug Release and Antigen-Specific In Vitro Anticancer Activity
- Antibody-Drug Conjugates for Cancer Therapy
- Design, Synthesis, and Biological Evaluation of Antibody-Drug Conjugates Comprised of Potent Camptothecin Analogues
技术文章
[Featured Products] Enzymatically Cleavable Linkers for Antibody-Drug Conjugates (ADCs)[TCIMAIL No.183] Dipeptides Degradable by Enzyme in Lysosome
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化学品安全说明书(SDS)
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技术规格
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