Maximum quantity allowed is 999
请选择数量
CAS RN: 2140-77-4 | 产品编码: M3745
N2-Methylguanosine
×
![]()
×
New
纯度/分析方法: >95.0%(HPLC)(qNMR)
别名：
- N2-甲基鸟苷
- 9-[(2R,3R,4S,5R)-3,4-二羟基-5-(羟甲基)四氢呋喃-2-基]-2-(甲基氨基)-1,9-二氢-6H-嘌呤-6-酮
- 9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-2-(methylamino)-1,9-dihydro-6H-purin-6-one
产品文档：
| 产品编码 | M3745 |
纯度/分析方法 
|
>95.0%(HPLC)(qNMR) |
| 分子式/分子量 | C__1__1H__1__5N__5O__5 = 297.27 |
| 外观与形状（20°C） | 固体 |
| 储存温度
|
冷藏 (0-10°C) |
| 储存在惰性气体下 | 存放于惰性气体之中 |
| 应避免的情况 | 空气,湿气 (吸湿),加热 |
| 包装和容器
|
50MG-Glass Bottle with Plastic Insert （查看图片） |
| CAS RN | 2140-77-4 |
| Reaxys-RN | 46491 |
| MDL编号 | MFCD00057039 |
技术规格
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(qNMR) | min. 95.0 % |
| NMR | confirm to structure |
物性（参考值）
| 熔点 | 233 °C |
GHS
相关法规
运输信息
| HS编码* | 2934.99-000 |
应用
N2-Methylguanosine: A Modified Nucleoside Found in the tRNA of Nearly All Archaea and Eukaryotes
N2-Methylguanosine (m2G) is a modified nucleoside found in the tRNA of nearly all archaea and eukaryotes but not in bacteria. It plays crucial roles in the control and stabilization of tRNA.1-3) In addition, it has been reported that some modified nucleosides, including N2-methylguanosine, are excreted in abnormal amounts in the urine of patients with malignancies. Thus, the modified nucleosides may be useful tumor markers.4,5)
References
- 1) Trm11p and Trm112p are both required for the formation of 2-methylguanosine at position 10 in yeast tRNA
- 2) Formation of m2G6 in Methanocaldococcus jannaschii tRNA catalyzed by the novel methyltransferase Trm14
- 3) iRNA-m7G: Identifying N7-methylguanosine Sites by Fusing Multiple Features
- 4) Modified nucleosides: an accurate tumour marker for clinical diagnosis of cancer, early detection and therapy control
- 5) Liquid chromatography tandem mass spectrometry study of urinary nucleosides as potential cancer markers
产品文档 (部分产品的分析图谱无法提供，敬请谅解。)
化学品安全说明书(SDS)
请选择语言。
如需更多帮助，请联系我 们。
技术规格
CoA及其他文档
请输入批号
批号输入有误。请输入中横线前的4-5个字母数字字符。
示例 CoA
可下载CoA示例。注：该示例不一定是最新批次的CoA。
目前没有该产品的 CoA 示例。
分析图谱
请输入批号
批号输入有误。请输入中横线前的4-5个字母数字字符。
很抱歉，您搜索的分析图谱无法提供。