Maximum quantity allowed is 999
请选择数量
CAS RN: 95-54-5 | 产品编码: P0168
1,2-Phenylenediamine

技术规格
Appearance | White to Light gray to Light orange powder to crystal |
Purity(GC) | min. 98.0 % |
Purity(Nonaqueous Titration) | min. 98.0 % |
Melting point | 100.0 to 105.0 °C |
物性(参考值)
熔点 | 103 °C |
沸点 | 265 °C |
水溶性 | 可溶 |
在水中的溶解度 | 41 g/l 35 °C |
溶解性(可溶于) | 丙酮, 苯 |
GHS
象形图 |
![]() ![]() ![]() |
信号词 | Danger |
危险性说明 | H330 : Fatal if inhaled. H302 + H312 : Harmful if swallowed or in contact with skin. H319 : Causes serious eye irritation. H371 : May cause damage to organs. H370 : Causes damage to organs. H373 : May cause damage to organs through prolonged or repeated exposure. H317 : May cause an allergic skin reaction. H341 : Suspected of causing genetic defects. H351 : Suspected of causing cancer. H410 : Very toxic to aquatic life with long lasting effects. |
防范说明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P272 : Contaminated work clothing should not be allowed out of the workplace. P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P271 : Use only outdoors or in a well-ventilated area. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P284 : Wear respiratory protection. P391 : Collect spillage. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. P362 + P364 : Take off contaminated clothing and wash it before reuse. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P302 + P352 + P312 : IF ON SKIN: Wash with plenty of water.Call a POISON CENTER/doctor if you feel unwell. P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor. P403 + P233 : Store in a well-ventilated place. Keep container tightly closed. P405 : Store locked up. |
相关法规
RTECS# | SS7875000 |
运输信息
UN编号 | UN1673 |
类别 | 6.1 |
包装类别 | III |
HS编码* | 2921.51-000 |
应用
One-pot Synthesis of Benzodiazepin Derivatives via Three-component Reaction
Reference
- A facile route to 1,5-benzodiazepin-2-yl-phosphonates via ytterbium chloride-catalyzed three-component reaction
应用
Synthesis of Benzimidazole Using Gold’s Reagent
A dry, three-necked, round-bottomed flask is equipped with a condenser, thermometer, magnetic stirrer and is placed under a nitrogen atmosphere. Into the flask is placed 100 mL of dry 1,4-dioxane along with 5.4 g (0.05 mol) of 1,2-phenylenediamine and 9.9 g (0.061 mol) of Gold’s reagent. The mixture is refluxed overnight, cooled to room temperature and 4.1 g (0.05 mol) of anhydrous sodium acetate and 2 mL of glacial acetic acid are added. The resulting mixture is refluxed for 3 hours, cooled to room temperature and the solvent is removed in vacuo. The residue is taken up in chloroform (100 mL), extracted with a saturated, aqueous solution of sodium bicarbonate (3 x 50 mL) and dried over anhydrous magnesium sulfate. After removing the drying agent by filtration, the chloroform extract is concentrated in vacuo to leave a solid which is collected by vacuum filtration with the aid of a small amount (15 mL) of water. The resulting benzimidazole amounts to 3.7 g (63% yield).
References
参考文献